Anti-Desmin Antibody (Monoclonal, DE-U-10)

Mouse IgG monoclonal antibody for Desmin , desmin (DES) detection. Tested with WB, IHC-P in Human;mouse;rat;rabbit. No cross reactivity with other proteins.

SKU MA1036
Size 100μg/vial
Reactivity Human, Mouse, Rabbit, Rat
Clonality Monoclonal
Clone Number DE-U-10
Host Mouse
Ig Isotype Mouse IgG1
Applications IHC, WB


Product Name Anti-Desmin Antibody (Monoclonal, DE-U-10)
See all Des primary antibodies, ELISA kits and proteins
SKU/Catalog Number MA1036
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100μg/vial
Description Monoclonal clone# G2 antibody for Desmin/DES detection. Host: Mouse.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Desmin/DES information: Molecular Weight: 53457 MW; Subcellular Localization: Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm . Cell membrane, sarcolemma . Localizes in the intercalated disks which occur at the Z line of cardiomyocytes.
Cite This Product Anti-Desmin Antibody (Monoclonal, DE-U-10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1036)
Specificity Anti-Desmin Antibody (Monoclonal, DE-U-10) (MA1036) reacts with Human, Mouse, Rabbit, Rat Des, in native form and recombinant. Superfamily members of Des are not reactive to MA1036.
Host Mouse
Contents/Buffer Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Form Lyophilized
Reconstitution Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Immunogen Desmin from pig stomach.
Reactivity Human, Mouse, Rabbit, Rat

Assay Details

Our Boster Quality Guarantee for Anti-Desmin Antibody (Monoclonal, DE-U-10) covers its use in the following applications.

*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.

Assay Dilutions Overview

Concentration: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Immunohistochemistry(Paraffin-embedded Section), 2-4μg/ml, Human, mouse, rat, rabbit, By Heat
Western blot, 2μg/ml, Human, mouse, rat, rabbit

Boster's Compatible Products

The following reagents are used to generate the images below for Anti-Desmin Antibody (Monoclonal, DE-U-10) (MA1036).

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Images And Assay Conditions


Anti-Desmin antibody (monoclonal), MA1036, IHC(P)
IHC(P): Rat Cardiac Muscle Tissue


Anti-Desmin antibody (monoclonal), MA1036, Western blotting
All lanes: Anti Desmin (MA1036) at 0.5ug/ml
Lane 1: Rat Skeletal Muscle Tissue Lysate at 50ug
Lane 2: Rat Cardiac Muscle Tissue Lysate at 50ug
Lane 3: Mouse Skeletal Muscle Tissue Lysate at 50ug
Lane 4: Mouse Cardiac Muscle Tissue Lysate at 50ug
Predicted bind size: 53KD
Observed bind size: 53KD

Target Info

Protein Target Info (Source:

Uniprot Id P48675
Gene Name Des
Protein Name Desmin
Alternative Names Desmin;Des;
Subcellular Localization Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm . Cell membrane, sarcolemma . Localizes in the intercalated disks which occur at the Z line of cardiomyocytes. .
Molecular Weight 53457 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.


Protein Function Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. .
Research Areas Human, Mouse, Rabbit, Rat

*You can search these to find other products in these research areas.
Background Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy.

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)



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Customer Q&As

  • Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
    A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
  • Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
    A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact [email protected]
  • Q: Can you provide monoclonal antibodies carrier free?
    A: For most of our monoclonal antibodies, we are unable to provide them carrier free. If you would like to check if a specific antibody can be provided carrier free, please send an email to [email protected]
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