Anti-DNMT3B Antibody Picoband™

Dynamin 2 antibody

Boster Bio Anti-DNMT3B Antibody Picoband™ catalog # A00319-5. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Product Info Summary

SKU: A00319-5
Size: 100 μg/vial
Reactive Species: Human, Monkey, Mouse, Rat
Host: Rabbit
Application: ELISA, Flow Cytometry, WB

Product Name

Anti-DNMT3B Antibody Picoband™

View all Dynamin 2 Antibodies

SKU/Catalog Number

A00319-5

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DNMT3B Antibody Picoband™ catalog # A00319-5. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-DNMT3B Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00319-5)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Immunogen

E.coli-derived human DNMT3B recombinant protein (Position: E271-E853).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00319-5 is reactive to DNMT3B in Human, Monkey, Mouse, Rat

Applications

A00319-5 is guaranteed for ELISA, Flow Cytometry, WB Boster Guarantee

Background of Dynamin 2

DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human, Monkey, Mouse, Rat
Flow Cytometry, 1-3 μg/1x106 cells, Human, Mouse, Rat
Direct ELISA, 0.1-0.5 μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For DNMT3B (Source: Uniprot.Org, NCBI)

Uniprot ID

P50570

Gene ID

1785

Gene Name

DNMT3B

Full Name

Dynamin-2

Weight

98.064kDa

Superfamily

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

CMTDI1CMT2M; CMTDIBdynamin II; DI-CMTB; DYN2EC 3.6.5.5; dynamin 2; dynamin-2; DYNII DNM2 CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5 dynamin 2 dynamin-2|dynamin II

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on DNMT3B, check out the DNMT3B Infographic

DNMT3B infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for DNMT3B: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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Total: $315

Size:100 μg

SKU:A00319-5

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A00319-5
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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