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Product Info Summary
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Boster Bio Anti-DR4/TNFRSF10A Antibody catalog # PA1975. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DR4/TNFRSF10A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1975)
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
A synthetic peptide corresponding to a sequence at the N-terminus of human DR4 (110-125aa TIKLHDQSIGTQQWEH).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
PA1975 is reactive to TNFRSF10A in Human
PA1975 is guaranteed for WB Boster Guarantee
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Validation Images & Assay Conditions
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Anti-DR4 antibody, PA1975, Western blotting
Lane 1: SW620 Cell Lysate
Lane 2: COLO320 Cell Lysate
Lane 3: HT1080 Cell Lysate
Gene/Protein Information For TNFRSF10A (Source: Uniprot.Org, NCBI)
Tumor necrosis factor receptor superfamily member 10A
APO2; CD261 antigen; CD261; cytotoxic TRAIL receptor; Death receptor 4; DR4 TRAIL receptor 1; DR4; TNF-related apoptosis inducing ligand receptor 1; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAILR1; TRAIL-R1; TRAILR-1; TRAILR1MGC9365; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily, member 10a TNFRSF10A APO2, CD261, DR4, TRAILR-1, TRAILR1 TNF receptor superfamily member 10a tumor necrosis factor receptor superfamily member 10A|TNF-related apoptosis-inducing ligand receptor 1|TRAIL receptor 1|TRAIL-R1|cytotoxic TRAIL receptor|death receptor 4|tumor necrosis factor receptor superfamily member 10a variant 2|tumor necrosis factor receptor superfamily, member 10a*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
For more info on TNFRSF10A, check out the TNFRSF10A Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for TNFRSF10A: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
PA1975 has been cited in 3 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Zhang L, Niu T, Yang Sy, Lu Z, Chen B. Spine (Phila Pa 1976). 2008 Feb 15;33(4):422-7. Doi: 10.1097/Brs.0B013E318163E036. The Occurrence And Regional Distribution Of Dr4 On Herniated Disc Cells: A Potential Apoptosis Pathway In Lumbar Intervertebr...
Fu K, Ren H, Wang Y, Fei E, Wang H, Wang G. Oncogene. 2012 Mar 8;31(10):1311-22. Doi: 10.1038/Onc.2011.315. Epub 2011 Jul 25. Dj-1 Inhibits Trail-Induced Apoptosis By Blocking Pro-Caspase-8 Recruitment To Fadd.
Liu N, Zuo C, Wang X, Chen T, Yang D, Wang J, Zhu H. Oncotarget. 2014 Jul 15;5(13):4959-71. Mir-942 Decreases Trail-Induced Apoptosis Through Isg12A Downregulation And Is Regulated By Akt.
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