Anti-ECT2 Antibody

ECT2 antibody

Boster Bio Anti-ECT2 Antibody (Catalog # M01862). Tested in WB application(s). This antibody reacts with Human.

Product Info Summary

SKU: M01862
Size: 50 µl
Reactive Species: Human
Host: Mouse
Application: WB

Product Name

Anti-ECT2 Antibody

View all ECT2 Antibodies

SKU/Catalog Number

M01862

Size

50 µl

Description

Boster Bio Anti-ECT2 Antibody (Catalog # M01862). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-ECT2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01862)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Monoclonal

Clone Number

1691CT516.3.3

Isotype

IgG1,k

Immunogen

This ECT2 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 200-460 amino acids from human ECT2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01862 is reactive to ECT2 in Human

Applications

M01862 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

103.505kDa

Background of ECT2

Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP. Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC, RAC1 and CDC42. Required for signal transduction pathways involved in the regulation of cytokinesis. Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Regulates the translocation of RHOA from the central spindle to the equatorial region. Plays a role in the control of mitotic spindle assembly; regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression. Involved in the regulation of epithelial cell polarity; participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner. Plays a role in the regulation of neurite outgrowth. Inhibits phenobarbital (PB)- induced NR1I3 nuclear translocation. Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells, thereby acting to coordinately drive tumor cell proliferation and invasion. Also stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For ECT2 (Source: Uniprot.org, NCBI)

Gene Name

ECT2

Full Name

Protein ECT2

Weight

103.505kDa

Alternative Names

ARHGEF31; epithelial cell transforming sequence 2 oncogene; Epithelial cell-transforming sequence 2 oncogene; FLJ10461; MGC138291; protein ECT2 ECT2 ARHGEF31 epithelial cell transforming 2 protein ECT2|epithelial cell-transforming sequence 2 oncogene

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ECT2, check out the ECT2 Infographic

ECT2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ECT2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01862-50ul

50 µl

$298
M01862-200ul

200 µl

$460

Free Secondary Antibody

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M01862
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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