Anti-EFEMP2 Antibody

Product Name

Anti-EFEMP2 Antibody

View all EFEMP2 Antibodies

SKU/Catalog Number

A05653

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-EFEMP2 Antibody (Catalog # A05653). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EFEMP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05653)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human EFEMP2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05653 is reactive to EFEMP2 in Human, Mouse

Applications

A05653 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

49.405kDa

Background of EFEMP2

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene.

Giltay R., Matrix Biol. 18:469-480(1999).
Zemel R., Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
Katsanis N., Hum. Genet. 106:66-72(2000).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

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Immunohistochemistry analysis of paraffin-embedded human placenta tissue using EFEMP2 antibody A05653.

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Western blot analysis of extracts from K562 cells and 3T3 cells, using EFEMP2 antibody A05653.

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Immunofluorescence analysis of A549 cells, using EFEMP2 antibody A05653.

Gene/Protein Information For EFEMP2 (Source: Uniprot.org, NCBI)

Alternative Names

EGF containing fibulin-like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2; FBLN4fibulin-4; FIBL-4; fibulin 4; Fibulin-4; MBP1; Protein UPH1; UPH1mutant p53 binding protein 1 EFEMP2 ARCL1B, FBLN4, MBP1, UPH1 EGF containing fibulin extracellular matrix protein 2 EGF-containing fibulin-like extracellular matrix protein 2|EGF containing fibulin like extracellular matrix protein 2|FIBL-4|fibulin 4|mutant p53 binding protein 1

For more info on EFEMP2, check out the EFEMP2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for EFEMP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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