Anti-EIF2 Alpha Eif2s1 Antibody

eIF2 alpha/EIF2S1 antibody

Boster Bio Anti-EIF2 Alpha Eif2s1 Antibody catalog # A04387. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A04387
Size: 50μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-EIF2 Alpha Eif2s1 Antibody

View all eIF2 alpha/EIF2S1 Antibodies

SKU/Catalog Number

A04387

Size

50μg/vial

Form

Liquid

Description

Boster Bio Anti-EIF2 Alpha Eif2s1 Antibody catalog # A04387. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EIF2 Alpha Eif2s1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04387)

Host

Rabbit

Contents

Each vial contains 0.09% sodium azide and 50% glycerol. 

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide corresponding to a portion of rat eIF2-alpha .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A04387 is reactive to EIF2S1 in Human, Mouse, Rat

Applications

A04387 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

36.112kDa

Background of eIF2 alpha/EIF2S1

EIF2S1 (Eukaryotic Translation Initiation Factor 2, Subunit 1), also called EIF2-alpha, is a protein that in humans is encoded by the EIF2S1 gene. Hartz (2010) mapped the EIF2S1 gene to chromosome 14q23.3 based on an alignment of the EIF2S1 sequence with the genomic sequence (GRCh37). Ernst et al. (1987) stated that protein synthesis is inhibited due to phosphorylation of Eif2-alpha in hemin-deprived rabbit reticulocyte lysates. HeLa cells subjected to heat shock, serum deprivation, or interferon treatment followed by virus infection also show a correlation between EIF2-alpha phosphorylation and translational repression. Jacob et al. (1989) found that the alpha-Pal transcription factor bound to 2 palindromic sites within the EIF2-alpha promoter and was essential for transcription of the EIF2-alpha gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1μg/ml, ECL, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For EIF2S1 (Source: Uniprot.org, NCBI)

Gene Name

EIF2S1

Full Name

Eukaryotic translation initiation factor 2 subunit 1

Weight

36.112kDa

Superfamily

eIF-2-alpha family

Alternative Names

eIF2 alpha; EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha; EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; EIF2S1 EIF2S1 EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A eukaryotic translation initiation factor 2 subunit alpha eukaryotic translation initiation factor 2 subunit 1|eIF-2-alpha|eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on EIF2S1, check out the EIF2S1 Infographic

EIF2S1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for EIF2S1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04387

200ug

$357

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