Anti-eIF4E3 Antibody

Product Name

Anti-eIF4E3 Antibody

View all Eif4e3 Antibodies

SKU/Catalog Number

A13024

Size

100μl

Form

Liquid

Description

Boster Bio Anti-eIF4E3 Antibody catalog # A13024. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-eIF4E3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13024)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

2H4

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human eIF4E3. at AA rangle: 110-190

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A13024 is reactive to Eif4e3 in Human, Mouse, Rat

Applications

A13024 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

22.836kDa

Background of Eif4e3

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of 3T3 cells using eIF4E3 Polyclonal antibody.

Gene/Protein Information For Eif4e3 (Source: Uniprot.org, NCBI)

Alternative Names

eIF4E type 3; eIF-4E type 3; eIF-4E3; eIF4E-3; eukaryotic translation initiation factor 4E family member 3; eukaryotic translation initiation factor 4E member 3; eukaryotic translation initiation factor 4E type 3; MGC39820; MGC86971

For more info on Eif4e3, check out the Eif4e3 Infographic

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In this infographic, you will see the following information for Eif4e3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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