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Product Info Summary
| SKU: | A02767-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-Ephrin-B1/2 (Q324) EFNB1 Antibody
SKU/Catalog Number
A02767-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Ephrin-B1/2 (Q324) EFNB1 Antibody catalog # A02767-1. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Ephrin-B1/2 (Q324) EFNB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02767-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TGFbeta RIII around the phosphorylation site of T842.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02767-1 is reactive to EFNB1 in Human, Mouse, Rat
Applications
A02767-1 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
38.007kDa
Background of EFNB1
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Cheung P.C.F., Biochem. J. 346:659-669(2000).
Lang T.M., Genomics 70:258-263(2000).
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Immunohistochemistry validation of EFNB1 using Anti-Ephrin-B1/2 (Q324) EFNB1 Antibody (A02767-1).
Immunohistochemistry (IHC) analyzes of Ephrin-B1/2 (Q324) pAb in paraffin-embedded human esophageal carcinoma tissue at 1:50.showing cytoplasmic staining. Negative control (the right)Using PBS instead of primary antibodyProtein Target Info & Infographic
Gene/Protein Information For EFNB1 (Source: Uniprot.org, NCBI)
Gene Name
EFNB1
Full Name
Ephrin-B1
Weight
38.007kDa
Superfamily
ephrin family
Alternative Names
Cek5-L; EFL3; EFL-3; EFNB1; ELK ligand; ELK-L; EphrinB1; Ephrin-B1; LERK-2; STRA-1 EFNB1 CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2 ephrin B1 ephrin-B1|ELK ligand|eph-related receptor tyrosine kinase ligand 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EFNB1, check out the EFNB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EFNB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ephrin-B1/2 (Q324) EFNB1 Antibody (A02767-1)
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No publications found for A02767-1
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