Product Info Summary
SKU: | A04496-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Exportin-2 CSE1L Antibody
View all CSE1L/CAS/Exportin-2 Antibodies
SKU/Catalog Number
A04496-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Exportin-2 CSE1L Antibody catalog # A04496-2. Tested in WB,ICC,IF,IHC,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Exportin-2 CSE1L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04496-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human FOXD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04496-2 is reactive to CSE1L in Human, Mouse, Rat
Applications
A04496-2 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
110.417kDa
Background of CSE1L/CAS/Exportin-2
Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Gregory S.G., Nature 441:315-321(2006).
Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).
Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1,000
ICC: 1:50-1:200
IHC: 1:50-1:200
FC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of CSE1L using Anti-Exportin-2 CSE1L Antibody (A04496-2).
ICC staining Cellular Apoptosis Susceptibility in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-Exportin-2 CSE1L Antibody A04496-2
Western blot analysis of Cellular Apoptosis Susceptibility on different lysates using anti-Cellular Apoptosis Susceptibility antibody at 1/500 dilution.Positive control:
Lane 1: Mouse testis
Lane 2: SiHa
Lane 3: SK-BR-3
Lane 4: PC-3M
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CSE1L (Source: Uniprot.org, NCBI)
Gene Name
CSE1L
Full Name
Exportin-2
Weight
110.417kDa
Superfamily
XPO2/CSE1 family
Alternative Names
CAS; CASMGC117283; Cellular apoptosis susceptibility protein; chromosome segregation 1 (yeast homolog)-like; Chromosome segregation 1-like protein; CSE1 chromosome segregation 1-like (yeast); CSE1; CSE1L; exp2; exportin-2; Importin-alpha re-exporter; MGC130037; XPO2; XPO2MGC130036 CSE1L CAS, CSE1, XPO2 chromosome segregation 1 like exportin-2|CSE1 chromosome segregation 1-like|cellular apoptosis susceptibility protein|chromosome segregation 1-like protein|epididymis secretory sperm binding protein|exp2|importin-alpha re-exporter
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CSE1L, check out the CSE1L Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CSE1L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Exportin-2 CSE1L Antibody (A04496-2)
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No publications found for A04496-2
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