Product Info Summary
SKU: | A00237-1 |
---|---|
Size: | 100μl |
Reactive Species: | Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-FADD Antibody
SKU/Catalog Number
A00237-1
Size
100μl
Form
Liquid
Description
Boster Bio Anti-FADD Antibody catalog # A00237-1. Tested in WB applications. This antibody reacts with Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FADD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00237-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from mouse FADD around the non-phosphorylation site of S191.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00237-1 is reactive to FADD in Mouse
Applications
A00237-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
23279 MW
Background of FADD
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Kozikowski AP, et al. (2006)ChemMedChem. 1(2):256-66.
Jakowec MW,et al.(2001)Dev Neurosci.23(2):91-9.
El-Agnaf OM,et al.(1998)FEBS Lett. 440(1-2):67-70.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis of HeLa cells using FADD Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For FADD (Source: Uniprot.org, NCBI)
Gene Name
FADD
Full Name
FAS-associated death domain protein
Weight
23279 MW
Alternative Names
FADD; Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; GIG3; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; MORT1Fas-associating protein with death domain; protein FADD FADD GIG3, MORT1 Fas associated via death domain FAS-associated death domain protein|Fas (TNFRSF6)-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FADD, check out the FADD Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FADD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FADD Antibody (A00237-1)
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No publications found for A00237-1
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