Product Info Summary
SKU: | A05079 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-Fatty aldehyde dehydrogenase Aldh3A2 Antibody
SKU/Catalog Number
A05079
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Fatty aldehyde dehydrogenase Aldh3A2 Antibody (Catalog # A05079). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Aldh3A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Fatty aldehyde dehydrogenase Aldh3A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05079)
Host
Rabbit
Contents
Aldh3A2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
Aldh3A2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Aldh3A2. The immunogen is located within the last 50 amino acids of Aldh3A2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.
Reactive Species
A05079 is reactive to ALDH3A2 in Human, Mouse
Applications
A05079 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
54.848kDa
Background of FALDH
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Aldh3A2 antibody can be used for detection of Aldh3A2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of Aldh3A2 in mouse liver lysate with Aldh3A2 antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ALDH3A2 (Source: Uniprot.org, NCBI)
Gene Name
ALDH3A2
Full Name
Aldehyde dehydrogenase family 3 member A2
Weight
54.848kDa
Superfamily
aldehyde dehydrogenase family
Alternative Names
Aldehyde dehydrogenase 10; aldehyde dehydrogenase 3 family, member A2; Aldehyde dehydrogenase family 3 member A2; ALDH10FLJ20851; EC 1.2.1; EC 1.2.1.3; FALDHDKFZp686E23276; fatty aldehyde dehydrogenase; Microsomal aldehyde dehydrogenase; SLS ALDH3A2 ALDH10, FALDH, SLS aldehyde dehydrogenase 3 family member A2 aldehyde dehydrogenase family 3 member A2|aldehyde dehydrogenase 10|fatty aldehyde dehydrogenase|microsomal aldehyde dehydrogenase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ALDH3A2, check out the ALDH3A2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ALDH3A2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Fatty aldehyde dehydrogenase Aldh3A2 Antibody (A05079)
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