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Product Info Summary
|Reactive Species:||Chicken, Human, Mouse|
|Application:||IHC, ICC, WB|
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Anti-Fibronectin Fn1 Monoclonal Antibody
Boster Bio Anti-Fibronectin Fn1 Monoclonal Antibody catalog # MA1116. Tested in IHC, ICC, WB applications. This antibody reacts with Chicken, Human, Mouse.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Fibronectin Fn1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1116)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Fibronectin from human plasma.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
MA1116 is reactive to Fn1 in Chicken, Human, Mouse
MA1116 is guaranteed for IHC, ICC, WB Boster Guarantee
Background of Fibronectin
Fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Cellular fibronectin is a 550KDa glycoprotein existing as two heterodimers, different from plasma fibronectin in the presence of additional polypeptide segments and in altering morphology of transformed cells and hemaglutination.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists world wide.
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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, chicken, mouse, By Heat
Immunocytochemistry , 1μg/ml, Human, chicken, mouse, -
Immunohistochemistry (Frozen Section), 1-2μg/ml, Human, chicken, mouse, -
Western blot, 1-2μg/ml, Human, chicken, mouse
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For Fn1 (Source: Uniprot.Org, NCBI)
CIG; ED-B; fibronectin 1; Fibronectin; FINC; FN; FN1; FNZ; GFND; GFND2; LETS; MSF; SMDCF Fn1|FIBNEC, fn-1|fibronectin 1|fibronectin|FN|fibronectin 2|fibronectin 3*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
For more info on Fn1, check out the Fn1 Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for Fn1: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
MA1116 has been cited in 26 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinase type I γ 90 activity and cell invasion
Zhang X,Ke PX,Yuan X,Zhang GP,Chen WL,Zhang GS. Forskolin Protected against Streptozotocin-Induced Diabetic Cardiomyopathy via Inhibition of Oxidative Stress and Cardiac Fibrosis in Mice. Biomed Res Int.2021 Jan 29;2021:8881843.doi:10.1155/2021/8881843.PM
MA1116 usage in article: APP:WB, SAMPLE:VENTRICULAR TISSUE, DILUTION:NA
Xu L,Sun N,Li G,Liu L.LncRNA H19 promotes keloid formation through targeting the miR-769-5p/EIF3A pathway.Mol Cell Biochem.2021 Jan 3.doi:10.1007/s11010-020-04024-x.Epub ahead of print.PMID:33389493.
MA1116 usage in article: APP:WB, SAMPLE:KELOID FIBROBLASTS, DILUTION:1:2000
Sang R,Liu Y,Kong L,Qian L,Liu C.Effect of Acellular Amnion With Increased TGF-β and bFGF Levels on the Biological Behavior of Tenocytes.Front Bioeng Biotechnol.2020 May 14;8:446.doi:10.3389/fbioe.2020.00446. PMID:32478059;PMCID:PMC7240037.
Species: Leghorn chicken
MA1116 usage in article: APP:IF, SAMPLE:ACELLULAR AMNIOTIC MEMBRANE, DILUTION:1:100
Glyceraldehyde-3-phosphate dehydrogenase acts as an adhesin in Erysipelothrix rhusiopathiae adhesion to porcine endothelial cells and as a receptor in %u2026
Rosiglitazone prevents advanced glycation end products%u2013induced renal toxicity likely through suppression of plasminogen activator inhibitor-1
Contribution of fibronectin-binding protein to pathogenesis of Streptococcus equi ssp . zooepidemicus
Elongation Factor Thermo Unstable (EF-Tu) Moonlights as an Adhesin on the Surface of Mycoplasma hyopneumoniae by Binding to Fibronectin
Pathophysiology of chronic pancreatitis induced by dibutyltin dichloride joint ethanol in mice
Wu Y, Wang Y, Ji Y, Ou Y, Xia H, Zhang B, Zhao Y. Am J Transl Res. 2017 Dec 15;9(12):5708-5718. eCollection 2017. C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cells
Fu Jr, Liu Wl, Zhou Yf, Zhou Jf, Sun Hy, Luo L, Zhang H, Xu Hz. Chin Med J (Engl). 2005 Dec 5;118(23):1979-86. Expansive Effects Of Aorta-Gonad-Mesonephros-Derived Stromal Cells On Hematopoietic Stem Cells From Embryonic Stem Cells.
Xue H, Zhang Yl, Liu Gs, Wang H. J Pharmacol Exp Ther. 2005 Nov;315(2):501-9. Epub 2005 Jul 28. A New Atp-Sensitive Potassium Channel Opener Protects The Kidney From Hypertensive Damage In Spontaneously Hypertensive Rats.
Yang Y, Gao X, Wang X, Su L, Xing H. Eur J Pharm Sci. 2012 Aug 30;47(1):75-83. Doi: 10.1016/J.Ejps.2012.05.005. Epub 2012 May 23. Total Flavonoids Of Fructus Chorspondiatis Inhibits Collagen Synthesis Of Cultured Rat Cardiac Fibroblasts Induced By...
Guo Y, Zeng Qc, Zhang Cq, Zhang Xz, Li Rx, Wu Jm, Guan J, Liu L, Zhang Xc, Li Jy, Wan Zm. Int J Med Sci. 2013 Nov 5;10(13):1837-45. Doi: 10.7150/Ijms.6786. Ecollection 2013. Extracellular Matrix Of Mechanically Stretched Cardiac Fibroblasts Improv...
Wang H, Wang Hs, Zhou Bh, Li Cl, Zhang F, Wang Xf, Zhang G, Bu Xz, Cai Sh, Du J. Plos One. 2013;8(2):E56664. Doi: 10.1371/Journal.Pone.0056664. Epub 2013 Feb 19. Epithelial-Mesenchymal Transition (Emt) Induced By Tnf-?? Requires Akt/Gsk-3??-Mediat...
Shi Z, Shen T, Liu Y, Huang Y, Jiao J. J Biol Chem. 2014 Mar 7;289(10):6415-28. Doi: 10.1074/Jbc.M113.515601. Epub 2014 Jan 23. Retinoic Acid Receptor ?? (Rarg) And Nuclear Receptor Subfamily 5, Group A, Member 2 (Nr5A2) Promote Conversion Of Fibr...
Gai X, Lu Z, Tu K, Liang Z, Zheng X. Plos One. 2014 Jan 13;9(1):E84551. Doi: 10.1371/Journal.Pone.0084551. Ecollection 2014. Caveolin-1 Is Up-Regulated By Gli1 And Contributes To Gli1-Driven Emt In Hepatocellular Carcinoma.
Xia H, Cheung Wk, Sze J, Lu G, Jiang S, Yao H, Bian Xw, Poon Ws, Kung Hf, Lin Mc. J Biol Chem. 2010 Nov 19;285(47):36995-7004. Doi: 10.1074/Jbc.M110.133744. Epub 2010 Sep 7. Mir-200A Regulates Epithelial-Mesenchymal To Stem-Like Transition Via Zeb...
Li T, Yang Z, Cai Hj, Song Lw, Lu Ky, Zhou Z, Wu Zd. World J Gastroenterol. 2010 Feb 14;16(6):749-54. Effects Of In Vitro Cultivated Calculus Bovis Compound On Pulmonary Lesions In Rabbits With Schistosomiasis.
Cheng Y, Wang Y, Kang Yz, Hu Py, Gao Y, Pan Mx. Digestion. 2013;87(3):189-95. Doi: 10.1159/000349949. Epub 2013 May 1. In Vitro Culture Of Tumour-Derived Hepatocytes In Decellularised Whole-Liver Biological Scaffolds.
Wu Y, Chen W, Guo M, He Q, Hu Y. Int J Clin Exp Pathol. 2014 Jul 15;7(8):4827-36. Ecollection 2014. Effects Of Transforming Growth Factor-??2 On Myocilin Expression And Secretion In Human Primary Cultured Trabecular Meshwork Cells.
Gong X, Liu H, Ding X, Liu M, Li X, Zheng L, Jia X, Zhou G, Zou Y, Li J, Huang X, Fan Y. Biomaterials. 2014 Jun;35(17):4782-91. Doi: 10.1016/J.Biomaterials.2014.02.050. Epub 2014 Mar 15. Physiological Pulsatile Flow Culture Conditions To Generate ...
Xiao H, Ji Am, Li Zl, Song Xd, Su D, Chen Ah. Sheng Li Xue Bao. 2008 Jun 25;60(3):355-61. Interleukin-1?? Inhibits Collagen Synthesis And Promotes Its Decomposition In Cultured Cardiac Fibroblasts.
Zhang H, Teng X, Liu Z, Zhang L, Liu Z. J Exp Clin Cancer Res. 2015 Feb 12;34:16. Doi: 10.1186/S13046-015-0132-Y. Gene Expression Profile Analyze The Molecular Mechanism Of Cxcr7 Regulating Papillary Thyroid Carcinoma Growth And Metastasis.
Zhang W, Chen Dq, Qi F, Wang J, Xiao Wy, Zhu Wz. J Cardiovasc Pharmacol. 2010 Jan;55(1):96-105. Doi: 10.1097/Fjc.0B013E3181C9548B. Inhibition Of Calcium-Calmodulin-Dependent Kinase Ii Suppresses Cardiac Fibroblast Proliferation And Extracellular M...
Sasaki M, Inoue M, Katada Y, Taguchi T. J Mater Sci Mater Med. 2013 Apr;24(4):951-8. Doi: 10.1007/S10856-012-4845-6. Epub 2013 Jan 19. Promotion Of Initial Cell Adhesion On Trisuccinimidyl Citrate-Modified Nickel-Free High-Nitrogen Stainless Steel.
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