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- Table of Contents
Fibronectin Antibodies
AND FN1 ELISA kits, Fibronectin Proteins
Many biological assays use antibodies to detect Fibronectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fibronectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fibronectin antibodies...
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FN1 Infographic by Boster Bio
All FN1 Products
Product
Figures
Specificity
Applications
Price
Human Fibronectin ELISA Kit PicoKine®
22 Citations 7 Q&As
Human
ELISA
$499
Cat # EK0349
96 wells/kit, with removable strips.
Cat # EK0349
96 wells/kit, with removable strips.
Rat Fibronectin ELISA Kit PicoKine®
10 Citations 5 Q&As
Rat
ELISA
$499
Cat # EK0350
96 wells/kit, with removable strips.
Cat # EK0350
96 wells/kit, with removable strips.
Mouse Fibronectin ELISA Kit PicoKine®
12 Citations 12 Q&As
Mouse
ELISA
$499
Cat # EK0351
96 wells/kit, with removable strips.
Cat # EK0351
96 wells/kit, with removable strips.
Anti-Fibronectin Fn1 Monoclonal Antibody
8 Citations 16 Q&As
Chicken, Human, Mouse
IHC, ICC, WB
$370
Cat # MA1116
100 μg/vial
Cat # MA1116
100 μg/vial
Bovine, Human, Monkey, Mouse, Rat
ELISA, IP, IHC, WB
$631
Cat # B00564
100ug
Cat # B00564
100ug
Anti-Fibronectin FN1 Rabbit Monoclonal Antibody
6 Citations 16 Q&As
Human
IF, IHC, ICC, WB
$370
Cat # M00564-1
100 μl
Cat # M00564-1
100 μl
Human
ELISA
$500
Cat # EZ0349
For 5 plates, 96 wells each
Cat # EZ0349
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # FEK0351
96 wells/kit, with removable strips.
Cat # FEK0351
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # FEK0350
96 wells/kit, with removable strips.
Cat # FEK0350
96 wells/kit, with removable strips.
Anti-Fibronectin/FN1 Antibody Picoband®
4 Citations 5 Q&As
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00564-1
100 μg/vial
Cat # A00564-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # M00564-2
100ul
Cat # M00564-2
100ul
Anti-Fibronectin Rabbit Monoclonal Antibody
41 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00564-3
100 μl/vial
Cat # M00564-3
100 μl/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00564-3
100 µg/vial
Cat # A00564-3
100 µg/vial
Human Fibronectin PicoKine® Quick ELISA Kit
1 Citations
Human
ELISA
$499
Cat # FEK0349
96 wells/kit, with removable strips.
Cat # FEK0349
96 wells/kit, with removable strips.
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00564-5
100 μg
Cat # M00564-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00564-6
100 μg
Cat # M00564-6
100 μg
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00564-7
20μL, 40μL, 100μL, 200μL
Cat # M00564-7
20μL, 40μL, 100μL, 200μL
FN1 Overview
Facts about Fibronectin.
Fibronectin (FN1)
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape.
Involved in osteoblast compaction throughout the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Gene Information
| Human | |
|---|---|
| Gene Name: | FN1 |
| Uniprot: | P02751 |
| Entrez: | 2335 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CIG; ED-B; fibronectin 1; Fibronectin; FINC; FN; FN1; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Molecular Weight
Mass (kDA):
272.32 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q35 |
| Sequence: | 2; NC_000002.12 (215360440..215436167, complement) |
Tissue Specificity
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Carcinoma
- Cell Invasion
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasm Invasiveness
- Fibrosis
- Inflammation
- Malignant Squamous Cell Neoplasm
- Thyroid Neoplasm
Interacting Proteins
- COL1A1
- COL5A1
- CTGF
- DCN
- FBN1
- FBN2
- FYN
- LOX
- LPA
- SCGB1A1
Pathways
- Cell Adhesion
- Pathogenesis
- Cell Migration
- Cell Proliferation
- Cell Cycle
- Angiogenesis
- Aging
- Cell Motility
- Regeneration
- Cell Differentiation
- Cell-matrix Adhesion
- Immune Response
- Osteoblast Differentiation
PTMs
- Phosphorylation
- Glycosylation
Research Areas
- Cancer
- Cellular Markers
- Mesenchymal Stem Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FN1
bosterbio.com/bosterbio-gene-info-cards/FN1
References
PMID: 11737888 by Schor S.L., et al. Phenotypic and genetic alterations in mammary stroma: implications for tumour progression.
PMID: 16322219 by Kay R.A., et al. The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3'-untranslated region-dependent nuclear sequestration of its precursor messenger RNA.
99 Publications of Boster Fibronectin Antibodies & ELISA Kits
- PubMed ID: PMID:29312523, C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cel...
- PubMed ID: PMID:26617787, RAC1 overexpression promotes the proliferation, migration and epithelial-mesench...
- PubMed ID: PMID:25197353, Effects of transforming growth factor-β2 on myocilin expression and secretion i...
- PubMed ID: PMID:16191423, Protective effects of blocking renin-angiotensin system on the progression of re...
- PubMed ID: 10.3892/ijo.2016.3343, Overexpression of SDF-1 activates the NF-κB pathway to induce epithelial to mes...
- PubMed ID: 10.3892/etm.2021.9764, Ginkgo biloba leaf extract prevents diabetic nephropathy through the s...
- PubMed ID: 10.3892/etm.2018.6995, Thalidomide decreases high glucose‑induced extracellular matrix protein synthe...
- PubMed ID: 10.3390/ijms20030585, Impact of Mechanical Load on the Expression Profile of Synovial Fibroblasts from...
- PubMed ID: 10.3389/fphar.2018.00628, A Chinese Herbal Formula Ameliorates Pulmonary Fibrosis by Inhibiting Oxidative ...
- PubMed ID: 10.2337/db17-0538, RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming ...
- PubMed ID: 10.1681/ASN.2015080889, Blockade of Orai1 Store-Operated Calcium Entry Protects against Renal Fibrosis
- PubMed ID: 10.1371/journal.pone.0174471, SnoN upregulation ameliorates renal fibrosis in diabetic nephropathy
- PubMed ID: 10.1248/bpb.b15-00127, Relaxin Inhibits High Glucose-Induced Matrix Accumulation in Human Mesangial Cel...
- PubMed ID: 10.1155/2021/8475868, PERK-Dependent Activation of the JAK2/STAT3 Pathway Contributes to High Glucose-...
- PubMed ID: 10.1152/ajprenal.00393.2016, Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAP...
- PubMed ID: 10.1152/ajpendo.00268.2017, ANRIL regulates production of extracellular matrix proteins and vasoactive facto...
- PubMed ID: 10.1124/jpet.105.089722, A New ATP-Sensitive Potassium Channel Opener Protects the Kidney from Hypertensi...
- PubMed ID: 10.1111/j.1440-1797.2005.00412.x, Role of impaired peritubular capillary and hypoxia in progressive interstitial f...
- PubMed ID: 10.1111/bcpt.12616, Placental Growth Factor Triggers Epithelial‐to‐Mesenchymal Transition‐like...
- PubMed ID: 10.1111/aas.13060, Early prognostic factors in septic shock cancer patients: a prospective study wi...
- PubMed ID: 10.1096/fj.201800296R, Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinas...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page