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Product Info Summary
| SKU: | M00011-3 |
|---|---|
| Size: | 100 μl/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-FOXP3 Rabbit Monoclonal Antibody
SKU/Catalog Number
M00011-3
Size
100 μl/vial
Form
Liquid
Description
Boster Bio Anti-FOXP3 Rabbit Monoclonal Antibody catalog # M00011-3. Tested in WB, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FOXP3 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00011-3)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
17F26
Isotype
IgG
Immunogen
A synthesized peptide derived from human FOXP3
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00011-3 is reactive to Foxp3 in Human
Applications
M00011-3 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
54 kDa
Calculated molecular weight
47.346kDa
Background of Foxp3
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994). The GluR1 subunit is widely expressed throughout the nervous system. Phosphorylation of Ser-845 on GluR1 is thought to be mediated by PKA and phosphorylation of this site increases the conductance of the AMPAR (Roche et al., 1996; Banke et al., 2000). In addition, phosphorylation of this site has been linked to synaptic plasticity as well as learning and memory (Lee at al., 2003; Esteban at al., 2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:50-1:200
Validation Images & Assay Conditions
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Immunohistochemical analysis of paraffin-embedded Human squamous carcinoma, using the Antibody at 1:100 dilution.
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Western blot analysis of FOXP3 expression in 293T cell lysate transfected with FOXP3.
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Immunohistochemical analysis of paraffin-embedded Human tongue cancer, using the Antibody at 1:100 dilution.
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Immunohistochemical analysis of paraffin-embedded Human Hodgkin's lymphoma, using the Antibody at 1:300 dilution.
Protein Target Info & Infographic
Gene/Protein Information For Foxp3 (Source: Uniprot.org, NCBI)
Gene Name
Foxp3
Full Name
Forkhead box protein P3
Weight
47.346kDa
Alternative Names
AIID; AIIDMGC141961; human foxp3; mouse foxp3; DIETER; forkhead box P3; Forkhead Box Protein P3; foxp3 ihc; foxp3 paraffin; FoxP3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; IPEX; JM2; MGC141961; MGC141963; PIDX; PIDXMGC141963; SCURFIN; XPID; XPIDpolyendocrinopathy, enteropathy, X-linked Foxp3|JM2, scu, scurfin, sf|forkhead box P3|forkhead box protein P3|scurfy
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Foxp3, check out the Foxp3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Foxp3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FOXP3 Rabbit Monoclonal Antibody (M00011-3)
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No publications found for M00011-3
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Customer Reviews
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