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Product Info Summary
| SKU: | A12703 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-FOXRED2 Antibody
SKU/Catalog Number
A12703
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FOXRED2 Antibody (Catalog # A12703). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
FOXRED2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FOXRED2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12703)
Host
Rabbit
Contents
FOXRED2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
FOXRED2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FOXRED2. The immunogen is located within amino acids 70 - 120 of FOXRED2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
AP3M1 antibody may cross-react with AP3M2.
Reactive Species
A12703 is reactive to FOXRED2 in Human
Applications
A12703 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
77.791kDa
Background of FOXRED2
FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FOXRED2 antibody can be used for detection of FOXRED2 by Western blot at 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FOXRED2 in human lung tissue lysate with FOXRED2 antibody at 1 μg/mL.
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Immunofluorescence of FOXRED2 in human lung cells with FOXRED2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For FOXRED2 (Source: Uniprot.org, NCBI)
Gene Name
FOXRED2
Full Name
FAD-dependent oxidoreductase domain-containing protein 2
Weight
77.791kDa
Superfamily
FOXRED2 family
Alternative Names
Endoplasmic reticulum flavoprotein associated with degradation; ERFAD; FAD-dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain-containing protein 2; FLJ23322; FLJ33734 FOXRED2 ERFAD FAD dependent oxidoreductase domain containing 2 FAD-dependent oxidoreductase domain-containing protein 2|ER flavoprotein associated with degradation|endoplasmic reticulum flavoprotein associated with degradation
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FOXRED2, check out the FOXRED2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FOXRED2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FOXRED2 Antibody (A12703)
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Customer Reviews
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