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Product Info Summary
| SKU: | A04752S434 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-GABAA R Beta 1 (phospho-S434) GABRB1 Antibody
View all GABA-A R beta 1 Antibodies
SKU/Catalog Number
A04752S434
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GABAA R Beta 1 (phospho-S434) GABRB1 Antibody catalog # A04752S434. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GABAA R Beta 1 (phospho-S434) GABRB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04752S434)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04752S434 is reactive to GABRB1 in Human, Mouse, Rat
Applications
A04752S434 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
54.235kDa
Background of GABA-A R beta 1
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Collins AL, et al. (2006) Neurogenetics ;7(3):167-174.
Ma DQ, et al. (2005) Am J Hum Genet ;77(3):377-388.
Edenberg HJ, et al. (2004) Am J Hum Genet ;74(4):705-714.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Immunohistochemistry (IHC) analyzes of p-GABAA Rβ1 (S434) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.
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Western blot (WB) analysis of p-GABAA Rβ1 (S434) polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264.7 whole cell lysate
Lane3:Rat brain tissue lysate
Protein Target Info & Infographic
Gene/Protein Information For GABRB1 (Source: Uniprot.org, NCBI)
Gene Name
GABRB1
Full Name
Gamma-aminobutyric acid receptor subunit beta-1
Weight
54.235kDa
Superfamily
ligand-gated ion channel (TC 1.A.9) family
Alternative Names
GABA A R beta 1; GABA(A) receptor subunit beta-1; GABAAR beta 1; GABAARb1; GABRB1; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid receptor subunit beta-1 GABRB1 DEE45, EIEE45 gamma-aminobutyric acid type A receptor subunit beta1 gamma-aminobutyric acid receptor subunit beta-1|gamma-aminobutyric acid (GABA) A receptor, beta 1|gamma-aminobutyric acid type A receptor beta1 subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GABRB1, check out the GABRB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GABRB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GABAA R Beta 1 (phospho-S434) GABRB1 Antibody (A04752S434)
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No publications found for A04752S434
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