Product Info Summary
SKU: | A04300 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-GALNT3 Antibody
View all Polypeptide GalNac Transferase 3/GALNT3 Antibodies
SKU/Catalog Number
A04300
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GALNT3 Antibody catalog # A04300. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GALNT3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04300)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human JAM-B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04300 is reactive to GALNT3 in Human, Mouse, Rat
Applications
A04300 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
72.61kDa
Background of Polypeptide GalNac Transferase 3/GALNT3
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-GALNT3 Antibody A04300
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For GALNT3 (Source: Uniprot.org, NCBI)
Gene Name
GALNT3
Full Name
Polypeptide N-acetylgalactosaminyltransferase 3
Weight
72.61kDa
Superfamily
glycosyltransferase 2 family
Alternative Names
EC 2.4.1.41; GalNAc transferase 3; GalNAc-T3; GalNAc-T3DKFZp686C10199; GALNT3; HFTC; HFTCMGC61909; HHS; HHSPolypeptide GalNAc transferase 3; polypeptide GalNAc-transferase T3; polypeptide N-acetylgalactosaminyltransferase 3; pp-GaNTase 3; Protein-UDP acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 3 (GalNAc-T3) GALNT3 GalNAc-T3, HFTC, HFTC1, HHS polypeptide N-acetylgalactosaminyltransferase 3 polypeptide N-acetylgalactosaminyltransferase 3|GalNAc transferase 3|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)|polypeptide GalNAc transferase 3|polypeptide GalNAc-transferase T3|pp-GaNTase 3|protein-UDP acetylgalactosaminyltransferase 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GALNT3, check out the GALNT3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GALNT3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GALNT3 Antibody (A04300)
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No publications found for A04300
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