Product Info Summary
SKU: | A03282 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-Girdin CCDC88A Antibody
SKU/Catalog Number
A03282
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Girdin CCDC88A Antibody (Catalog # A03282). Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Girdin CCDC88A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03282)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human Girdin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03282 is reactive to CCDC88A in Human
Applications
A03282 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
216042 MW
Background of Girdin
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation By similarity. Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Girdin antibody A03282.
Protein Target Info & Infographic
Gene/Protein Information For CCDC88A (Source: Uniprot.org, NCBI)
Gene Name
CCDC88A
Full Name
Girdin
Weight
216042 MW
Superfamily
CCDC88 family
Alternative Names
Akt phosphorylation enhancer; APE; APEGIRDIN; CCDC88A; coiled-coil domain containing 88A; Coiled-coil domain-containing protein 88A; G alpha-interacting vesicle-associated protein; G{alpha}-interacting vesicle-associated protein; Girders of actin filament; Girdin; GIV; GIVFLJ10392; GRDN; GRDNAKT-phosphorylation enhancer; HkRP1; HkRP1Galpha-interacting vesicle-associated protein; Hook-related protein 1; KIAA1212DKFZp686D0630 CCDC88A APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, PEHO, PEHOL coiled-coil domain containing 88A girdin|AKT-phosphorylation enhancer|Hook-related protein 1|g alpha-interacting vesicle-associated protein|girders of actin filaments
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCDC88A, check out the CCDC88A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCDC88A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Girdin CCDC88A Antibody (A03282)
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No publications found for A03282
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