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- Table of Contents
SLC2A4 Antibodies
AND SLC2A4 ELISA kits, SLC2A4 Proteins
Many biological assays use antibodies to detect SLC2A4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC2A4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC2A4 antibodies...
Designing a Western blot for SLC2A4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC2A4 Western Blot GuideSLC2A4 Infographic by Boster Bio
All SLC2A4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9109
100 μg/vial
Cat # PB9109
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1722
100 μg/vial
Cat # PA1722
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M00528S488
100 µl/vial
Cat # M00528S488
100 µl/vial
SLC2A4 Overview
Facts about Solute carrier family 2, facilitated glucose transporter member 4.
Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4)
Insulin-regulated facilitative glucose transporter. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC2A4 |
| Uniprot: | P14672 |
| Entrez: | 6517 |
Family
| Belongs to: |
|---|
| major facilitator superfamily |
Alternative Names
Glut4; GLUT-4; GLUT4Glucose transporter type 4, insulin-responsive; insulin-responsive glucose transporter type 4; SLC2A4; solute carrier family 2 (facilitated glucose transporter), member 4; solute carrier family 2, facilitated glucose transporter member 4
Molecular Weight
Mass (kDA):
54.787 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (7281718..7288257) |
Tissue Specificity
Skeletal and cardiac muscles; brown and white fat.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (PubMed:8300557). The dileucine internalization motif is critical for intracellular sequestration (PubMed:8300557). Insulin stimulation induces translocation to the cell membrane (By similarity).
Diseases
- Insulin Resistance
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Insulin Sensitivity
- Hyperinsulinism
- Diabetes Mellitus, Experimental
- Hyperglycemia
- Impaired Glucose Tolerance
- Hypertrophy
- Hypoxia
- Hypertensive Disease
Pathways
- Transport
- Glucose Transport
- Glucose Homeostasis
- Localization
- Secretion
- Exocytosis
- Endocytosis
- Pathogenesis
- Insulin Secretion
- Fatty Acid Oxidation
- Regulation Of Glucose Transport
- Swimming
- Glycolysis
PTMs
- Phosphorylation
- Oxidation
- Biotinylation
- Dephosphorylation
- Cleavage
- Glycosylation
- Carboxylation
- Myristoylation
- Ribosylation
- Reduction
Research Areas
- Diabetes Research
- Lipid and Metabolism
- Membrane Trafficking and Chaperones
- Neuroendocrinology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC2A4
bosterbio.com/bosterbio-gene-info-cards/SLC2A4
References
PMID: 2656669 by Fukumoto H., et al. Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin- responsive tissues.
PMID: 1397719 by Buse J.B., et al. Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
9 Publications of Boster SLC2A4 Antibodies & ELISA Kits
- PubMed ID: PMID:26550236, Vibration exercise decreases insulin resistance and modulates the insulin signal...
- PubMed ID: 10.1039/C6RA17654B, Microwave-assisted synthesis of chitooligosaccharide guanidine and its effect on...
- PubMed ID: 10.1016/j.anireprosci.2019.05.006, Effect of maternal feed restriction in dairy goats at different stages of gestat...
- PubMed ID: 30733181, Mo Z,Li L,Yu H,Wu Y,Li H.Coumarins ameliorate diabetogenic action of dexamethaso...
- PubMed ID: 30733181, Coumarins ameliorate diabetogenic action of dexamethasone via Akt activation and...
- PubMed ID: 29845188, lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPAR? p...
- PubMed ID: 27738449, Acupuncture Alters Expression of Insulin Signaling Related Molecules and Improve...
- PubMed ID: 29311680, Wei W, An XR, Jin SJ, Li XX, Xu M. Sci Rep. 2018 Jan 8;8(1):9. doi: 10.1038/s415...
- PubMed ID: 25774202, Zhou X, Wu W, Chen J, Wang X, Wang Y. Nutr Metab (Lond). 2015 Mar 8;12:10. Doi: ...
*More publications can be found for each product on its corresponding product page