Anti-Glutaredoxin 2/GLRX2 Antibody

Glutaredoxin 2 antibody

Boster Bio Anti-Glutaredoxin 2/GLRX2 Antibody catalog # PA1885. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PA1885
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Glutaredoxin 2/GLRX2 Antibody

View all Glutaredoxin 2 Antibodies

SKU/Catalog Number

PA1885

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Glutaredoxin 2/GLRX2 Antibody catalog # PA1885. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Glutaredoxin 2/GLRX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1885)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.01mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Glutaredoxin 2, different from the related rat sequence by two amino acids, and from the related mouse sequence by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1885 is reactive to GLRX2 in Human, Mouse, Rat

Applications

PA1885 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

18 kDa

Calculated molecular weight

18.052kDa

Background of Glutaredoxin 2

GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins (e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al. (2001) and Gladyshev et al. (2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al. (2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon (exon 1B) located upstream from the first exon used by the GLRX2A transcript (exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al. (2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, By Heat

Validation Images & Assay Conditions

Gene/Protein Information For GLRX2 (Source: Uniprot.org, NCBI)

Gene Name

GLRX2

Full Name

Glutaredoxin-2, mitochondrial

Weight

18.052kDa

Superfamily

glutaredoxin family

Alternative Names

bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); glutaredoxin 2; glutaredoxin-2, mitochondrial; GRX2bA101E13.1 GLRX2 CGI-133, GRX2 glutaredoxin 2 glutaredoxin 2|bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2)|glutaredoxin (thioltransferase) 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GLRX2, check out the GLRX2 Infographic

GLRX2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GLRX2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1885 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT) and its role in a human T cell line continuously exposed to asbestos

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1 Customer Q&As for Anti-Glutaredoxin 2/GLRX2 Antibody

Question

We are currently using anti-Glutaredoxin 2/GLRX2 antibody PA1885 for human tissue, and we are well pleased with the IHC-P results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on bovine tissues as well?

D. Krishna

Verified customer

Asked: 2016-01-26

Answer

The anti-Glutaredoxin 2/GLRX2 antibody (PA1885) has not been tested for cross reactivity specifically with bovine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2016-01-26

Order DetailsPrice
PA1885

100μg

$370
PA1885-10ug

10μg sample (liquid)

$99
PA1885-Biotin

100 μg Biotin conjugated

$570
PA1885-Cy3

100 μg Cy3 conjugated

$570
PA1885-Dylight488

100 μg Dylight488 conjugated

$570
PA1885-Dylight550

100 μg Dylight550 conjugated

$570
PA1885-Dylight594

100 μg Dylight594 conjugated

$570
PA1885-FITC

100 μg FITC conjugated

$570
PA1885-HRP

100 μg HRP conjugated

$570
PA1885-APC

100 μg APC conjugated

$670
PA1885-PE

100 μg PE conjugated

$670
PA1885-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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