Anti-GOLPH1 ACBD3 Antibody

ACBD3 antibody

Boster Bio Anti-GOLPH1 ACBD3 Antibody (Catalog # A05645). Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A05645
Size: 0.1 mg
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-GOLPH1 ACBD3 Antibody

View all ACBD3 Antibodies

SKU/Catalog Number

A05645

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-GOLPH1 ACBD3 Antibody (Catalog # A05645). Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

GOLPH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-GOLPH1 ACBD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05645)

Host

Rabbit

Contents

GOLPH1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

GOLPH1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human GOLPH1. The immunogen is located within amino acids 50 - 100 of GOLPH1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05645 is reactive to ACBD3 in Human

Applications

A05645 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60.593kDa

Background of ACBD3

GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

GOLPH1 antibody can be used for detection of GOLPH1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ACBD3 (Source: Uniprot.org, NCBI)

Gene Name

ACBD3

Full Name

Golgi resident protein GCP60

Weight

60.593kDa

Alternative Names

acyl-CoA binding domain containing 3; Acyl-CoA-binding domain-containing protein 3; acyl-Coenzyme A binding domain containing 3; GCP60Golgi phosphoprotein 1; GOCAP1Peripheral benzodiazepine receptor-associated protein PAP7; golgi complex associated protein 1, 60kDa; Golgi complex-associated protein 1; Golgi resident protein GCP60; GOLPH1PBR- and PKA-associated protein 7; PAP7; PBR associated protein; peripherial benzodiazepine receptor associated protein; PKA (RIalpha)-associated protein ACBD3 GCP60, GOCAP1, GOLPH1, PAP7 acyl-CoA binding domain containing 3 Golgi resident protein GCP60|PBR- and PKA-associated protein 7|PKA (RIalpha)-associated protein|acyl-Coenzyme A binding domain containing 3|golgi complex associated protein 1, 60kDa|golgi phosphoprotein 1|peripheral benzodiazepine receptor-associated protein PAP7

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ACBD3, check out the ACBD3 Infographic

ACBD3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ACBD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Total: $449

SKU:A05645

Backordered.

Lead time for this item is typically 4-7 days

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A05645
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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