Anti-GPRASP1 Antibody

Product Name

Anti-GPRASP1 Antibody

View all GPRASP1 Antibodies

SKU/Catalog Number

A08358

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-GPRASP1 Antibody (Catalog # A08358). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

GPRASP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-GPRASP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08358)

Host

Rabbit

Contents

GPRASP1 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

GPRASP1 antibody was raised against a 15 amino acid peptide near the amino terminus of human GPRASP1. The immunogen is located within amino acids 260 - 310 of GPRASP1.

Cross-reactivity

GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.

Reactive Species

A08358 is reactive to GPRASP1 in Human, Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

156.9 kDa

Background of GPRASP1

The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08358 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

GPRASP1 antibody can be used for detection of GPRASP1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information GPRASP1

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