Product Info Summary
SKU: | A08358 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-GPRASP1 Antibody
SKU/Catalog Number
A08358
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-GPRASP1 Antibody (Catalog # A08358). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
GPRASP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-GPRASP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08358)
Host
Rabbit
Contents
GPRASP1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
GPRASP1 antibody was raised against a 15 amino acid peptide near the amino terminus of human GPRASP1. The immunogen is located within amino acids 260 - 310 of GPRASP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.
Reactive Species
A08358 is reactive to GPRASP1 in Human, Mouse
Applications
A08358 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
156.865kDa
Background of GPRASP1
The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GPRASP1 antibody can be used for detection of GPRASP1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GPRASP1 in A-20 cell lysate with GPRASP1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of GPRASP1 in human breast carcinoma tissue with GPRASP12 antibody at 5 μg/ml.
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Immunofluorescence of GPRASP1 in human breast carcinoma tissue with GPRASP1 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For GPRASP1 (Source: Uniprot.org, NCBI)
Gene Name
GPRASP1
Full Name
G-protein coupled receptor-associated sorting protein 1
Weight
156.865kDa
Superfamily
GPRASP family
Alternative Names
G protein-coupled receptor associated sorting protein 1; GASP1; GASPKIAA0443GASP-1; G-protein coupled receptor-associated sorting protein 1 GPRASP1 GASP, GASP-1, GASP1 G protein-coupled receptor associated sorting protein 1 G-protein coupled receptor-associated sorting protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GPRASP1, check out the GPRASP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GPRASP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GPRASP1 Antibody (A08358)
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No publications found for A08358
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Recommended Resources
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Customer Reviews
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