Anti-HAT HAT1 Antibody

Product Name

Anti-HAT HAT1 Antibody

View all KAT1 Antibodies

SKU/Catalog Number

A03596

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-HAT HAT1 Antibody (Catalog # A03596). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HAT HAT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03596)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human HAT.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03596 is reactive to HAT1 in Human, Mouse, Rat

Applications

A03596 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

49.513kDa

Background of KAT1

Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.

Claudia J. Schroder-Adams, Bulletin of Canadian Petroleum Geology, Sep 1997; 45: 356 - 376.
Pil-Hoon Park, Am J Physiol Gastrointest Liver Physiol, Dec 2005; 289: G1124 - G1136.
Claudia J. Schroeder-Adams, Palaios, Aug 1998; 13: 361 - 375.
L. J. Patric

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from K562 cells, using HAT antibody A03596.

Gene/Protein Information For HAT1 (Source: Uniprot.org, NCBI)

Alternative Names

EC 2.3.1.48; histone acetyltransferase 1; histone acetyltransferase type B catalytic subunit; KAT1 HAT1 KAT1 histone acetyltransferase 1 histone acetyltransferase type B catalytic subunit

For more info on HAT1, check out the HAT1 Infographic

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In this infographic, you will see the following information for HAT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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