Anti-HCAR2 Antibody

HM74A/PUMA-G/GPR109A/NIACR1 antibody

Boster Bio Anti-HCAR2 Antibody catalog # A02511. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat. Cited in 1 publication(s).

Product Info Summary

SKU: A02511
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, ICC, WB

Customers Who Bought This Also Bought

Product Name

Anti-HCAR2 Antibody

View all HM74A/PUMA-G/GPR109A/NIACR1 Antibodies

SKU/Catalog Number

A02511

Size

100ul

Form

Liquid

Description

Boster Bio Anti-HCAR2 Antibody catalog # A02511. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HCAR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02511)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

recombinant Protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02511 is reactive to Hcar2 in Human, Mouse, Rat

Applications

A02511 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

41.401kDa

Background of HM74A/PUMA-G/GPR109A/NIACR1

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For Hcar2 (Source: Uniprot.org, NCBI)

Gene Name

Hcar2

Full Name

Hydroxycarboxylic acid receptor 2

Weight

41.401kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

GPR109A; HCA2; HCAR2; HM74A; hydroxycarboxylic acid receptor 2; Niacr1; Nicotinic Acid Receptor; PUMAG Hcar2|Gpr1, Gpr10, Gpr109a, Gpr109b, HM74, Ni, Niacr1, PUMA, PUMA-G, Pum, Pumag, mHM74b|hydroxycarboxylic acid receptor 2|hydroxycarboxylic acid receptor 2|G protein-coupled receptor 109A|G protein-coupled receptor 109B|G-protein coupled receptor 109|G-protein coupled receptor HM74|interferon-gamma inducible gene, Puma-g|niacin receptor 1|nicotinic acid receptor|putative seven transmembrane spanning receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Hcar2, check out the Hcar2 Infographic

Hcar2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Hcar2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A02511 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome

Have you used Anti-HCAR2 Antibody?

Submit a review and receive an Amazon gift card.

  • $30 for a review with an image

Be the first to review Anti-HCAR2 Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

1 Customer Q&As for Anti-HCAR2 Antibody

Question

Has A02511 been confirmed for IHC, or if it is strictly WB?

Verified customer

Asked: 2019-08-20

Answer

The Anti-HCAR2 Antibody (A02511) was only validated for WB. We do not guarantee it will work for IHC.

Boster Scientific Support

Answered: 2019-08-21

Order DetailsPrice
A02511-100ul

100ul

$405

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
In stock
Order Product
A02511
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$405.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.