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- Table of Contents
LHCGR antibody (PA1552) performs well in IHC, WB and shows reactivity with Human, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 12 Publications
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Anti-hCG receptor antibody, PA1552, IHC(P)
IHC(P): Rat Ovary Tissue
IHC(P): Rat Ovary Tissue
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Anti-hCG receptor/LHCGR Antibody Picoband®
LHCGR antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Rat | Rabbit | IHC, WB |
Tested Applications
LHCGR antibody was positively detected by WB in:
MCF-7 Whole Cell
Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane
LHCGR antibody was positively detected by IHC in:
Rat Ovary Tissue
Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.
Recommend Dilution
Application
Dilution
Species
Immunohistochemistry (Paraffin-embedded Section)
0.5-1μg/ml
Rat, Human
Western blot
0.1-0.5μg/ml
Human, Rat
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Reactive Data
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IHC
IF
Rat
Tested
Recommend
Human
Predicted
Predicted
Monkey
Predicted
Predicted
Sheep
Predicted
Predicted
Dog
Predicted
Predicted
Product Information
Product Name
Anti-hCG receptor/LHCGR Antibody Picoband®
View all LHCGR Antibodies
View all LHCGR Antibodies
Form
Lyophilized
Uniprot
Gene ID
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Host
Rabbit
Contents
Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor, different from the relative rat sequence by two amino acids, mouse sequence by three amino acids.
Cross-Reactivity
No cross-reactivity with other proteins
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
78 kDa
Calculated Molecular Weight
78.6 kDa
Background of LHCGR
The luteinizing hormone/choriogonadotropin receptor is a member of a subfamily of G protein-coupled receptors (GPCR) characterized by the presence of a large N-terminal extracellular domain containing several leucine-rich repeats (LRR). This glycoprotein hormone receptor family has been named the LRR-containing GPCR (LGR) family. The LHCGR gene contains 11 exons and spans approximately 80 kb and it is mapped to chromosome 2p21. In the ovary, theca, stromal, late-stage (luteinizing) granulosa, and luteal cells contain LHCGR. In the testes, Leydig cells contain LHCRG.
Cite This Product
Anti-hCG receptor/LHCGR Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1552)
Antibody Homology Across Species
The results generated by this homology analysis tool for commonly used animal species are shown below. For unlisted species, please refer to the homology analysis between the immunogen sequence and the corresponding species.
A homology of ≥90% is recommended. Generally, higher homology indicates a greater potential for cross-species reactivity. However, protein expression levels may vary among different species, tissues, and cell types. Therefore, the homology analysis results are for reference only and do not guarantee antibody cross-reactivity or experimental performance.
Human
100%
High Homology
Monkey
100%
High Homology
Sheep
94%
High Homology
Dog
94%
High Homology
Rat
88%
Moderate Homology
Rabbit
88%
Moderate Homology
Cow
88%
Moderate Homology
Mouse
82%
Moderate Homology
Zebrafish
71%
Moderate Homology
Drosophila
29%
Low homology
Homology ≥ 90%High Homology
70% ≤ Homology < 90%Moderate Homology
Homology < 70%Low homology
Protocols
Western Blot protocol for LHCGR antibody
Immunohistochemistry (IHC) protocol for LHCGR antibody
Publications
Application:
Species:
HCG-responsive aldosteronoma with transient secretion during pregnancy confirmed through HCG-stimulated adrenal venous sampling
Published: 2023-02-28
Journal: Frontiers in Endocrinology
Application: IHC
Impact Factor: 5.20
Species: Human
PMID: 36926028
Exogenous cholesterol acquisition signaling in LH-responsive MA-10 Leydig cells and in adult mice.
Published: 2022-08-17
Journal: JOURNAL OF ENDOCRINOLOGY
Application: WB
Impact Factor: 4.67
Species: Mouse
PMID: 35900012
The Role of Inactivated NF-κB in Premature Ovarian Failure
Published: 2021-12-28
Journal: AMERICAN JOURNAL OF PATHOLOGY
Application: IHC,WB
Impact Factor: 4.31
Species: Mouse,Human
PMID: 34971586
Pregnancy and Live Birth In Women With Pathogenic LHCGR Variants Using Their Own Oocytes
Published: 2019-08-08
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Application: IF
Impact Factor: 5.61
Species: Human
PMID: 31393569
Mechanism of cadmium poisoning on testicular injury in mice
Published: 2019-05-30
Journal: Oncology Letters
Application: IHC
Impact Factor: 1.87
Species: Mouse
PMID: 31423163
Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles
Published: 2019-05-17
Journal: JOURNAL OF CELLULAR PHYSIOLOGY
Application: IHC
Impact Factor: 4.52
Species: Mouse
PMID: 31102283
The role of combining medroxyprogesterone 17-acetate with human menopausal gonadotropin in mouse ovarian follicular development
Published: 2018-03-13
Journal: Scientific Reports
Application: IHC
Impact Factor: 4.12
Species: Mouse
PMID: 29535409
Di (2-ethylhexyl) phthalate impairs steroidogenesis in ovarian follicular cells of prepuberal mice
Published: 2016-07-12
Journal: ARCHIVES OF TOXICOLOGY
Application: IHC
Impact Factor: 6.64
Species: Mouse
PMID: 27405655
Serum levels of sex hormones and expression of their receptors in thyroid tissue in female patients with various types of thyroid neoplasms
Published: 2014-09-18
Journal: PATHOLOGY RESEARCH AND PRACTICE
Impact Factor: 1.56
PMID: 25305147
Female hormone release of microencapsulated Xenopus laevis ovarian cells
Published: 2013-04-24
Journal: INTERNATIONAL JOURNAL OF PHARMACEUTICS
Application: IHC
Impact Factor: 3.46
Species: X. laevis
PMID: 23623793
Toxicological effects of acrylamide on the reproductive system of weaning male rats
Published: 2011-03-17
Journal: TOXICOLOGY AND INDUSTRIAL HEALTH
Application: IHC
Impact Factor: 0.92
Species: Rat
PMID: 21415092
Premeiotic fetal murine germ cells cultured in vitro form typical oocyte-like cells but do not progress through meiosis
Published: 2009-04-09
Journal: THERIOGENOLOGY
Application: IHC
Impact Factor: 2.04
Species: Mouse
PMID: 19361852
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Product Promise
We promise Anti-hCG receptor/LHCGR Antibody Picoband® performs excellently in relevant applications for IHC, WB. If it doesn't perform as promised, we will refund the product. Learn more
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PA1552
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 3, 2026