Anti-HLX/Hlx11 Antibody

Product Name

Anti-HLX/Hlx11 Antibody

View all HLX1 Antibodies

SKU/Catalog Number

A06177-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-HLX/Hlx11 Antibody catalog # A06177-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HLX/Hlx11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06177-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human HLX1. at AA rangle: 290-370

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06177-1 is reactive to HLX in Human, Mouse, Rat

Applications

A06177-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

50.789kDa

Background of HLX1

APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using HLX1 Polyclonal antibody.

Gene/Protein Information For HLX (Source: Uniprot.org, NCBI)

Alternative Names

H2.0 (Drosophila)-like homeo box 1; H2.0-like homeo box 1; H2.0-like homeo box-1; H2.0-like homeobox 1; H2.0-like homeobox protein; H2.0-like homeobox; HB24; HLX1H2.0-like homeobox 1 (Drosophila); Homeobox protein HB24; Homeobox protein HLX1 HLX HB241, HLX H2.0 like homeobox H2.0-like homeobox protein|H2.0-like homeo box-1|H2.0-like homeobox 1|homeobox protein HB24|homeobox protein HLX1

For more info on HLX, check out the HLX Infographic

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In this infographic, you will see the following information for HLX: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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