Anti-Homeobox protein CDX-2 CDX2 Antibody

Product Name

Anti-Homeobox protein CDX-2 CDX2 Antibody

View all CDX2 Antibodies

SKU/Catalog Number

A00877-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Homeobox protein CDX-2 CDX2 Antibody (Catalog # A00877-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Homeobox protein CDX-2 CDX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00877-1)

Host

Rabbit

Contents

CDX2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

CDX2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CDX2. The immunogen is located within amino acids 220 - 270 of CDX2.

Reactive Species

A00877-1 is reactive to CDX2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

33.5 kDa

Background of CDX2

CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00877-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CDX2 antibody can be used for detection of CDX2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information CDX2

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