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Product Info Summary
| SKU: | A00877-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Homeobox protein CDX-2 CDX2 Antibody
SKU/Catalog Number
A00877-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Homeobox protein CDX-2 CDX2 Antibody (Catalog # A00877-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CDX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Homeobox protein CDX-2 CDX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00877-1)
Host
Rabbit
Contents
CDX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
CDX2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CDX2. The immunogen is located within amino acids 220 - 270 of CDX2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IKK gamma has no cross response to IKK alpha or IKK beta.
Reactive Species
A00877-1 is reactive to CDX2 in Human, Mouse, Rat
Applications
A00877-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
33.52kDa
Background of CDX2
CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CDX2 antibody can be used for detection of CDX2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CDX2 in mouse brain tissue lysate with CDX2 antibody at 1 μg/mL.
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Immunohistochemistry of CDX2 in rat brain tissue with CDX2 antibody at 5 μg/mL.
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Immunofluorescence of CDX2 in rat brain tissue with CDX2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CDX2 (Source: Uniprot.org, NCBI)
Gene Name
CDX2
Full Name
Homeobox protein CDX-2
Weight
33.52kDa
Superfamily
Caudal homeobox family
Alternative Names
caudal type homeo box transcription factor 2; caudal type homeobox 2; Caudal-type homeobox protein 2; CDX2; CDX3; CDX-3; CDX3caudal type homeobox transcription factor 2; homeobox protein CDX-2 CDX2 CDX-3/AS, CDX3, CDX2 caudal type homeobox 2 homeobox protein CDX-2|caudal type homeobox transcription factor 2|caudal-type homeobox protein 2|homeobox protein miniCDX2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CDX2, check out the CDX2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CDX2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Homeobox protein CDX-2 CDX2 Antibody (A00877-1)
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No publications found for A00877-1
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