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Product Info Summary
| SKU: | M04307 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC-F, WB |
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Product info
Product Name
Anti-Hu CD123 Purified IL3RA Monoclonal Antibody
View all IL-3R alpha/CD123 Antibodies
SKU/Catalog Number
M04307
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD123 Purified IL3RA Monoclonal Antibody (Catalog# M04307). Tested in Flow Cytometry, IP, WB, IHC-F application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD123 Purified IL3RA Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04307)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
6H6
Isotype
Mouse IgG1
Immunogen
IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells. The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M04307 is reactive to IL3RA in Human
Applications
M04307 is guaranteed for Flow Cytometry, IP, IHC-F, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
43.33kDa
Background of IL-3R alpha/CD123
CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For IL3RA (Source: Uniprot.org, NCBI)
Gene Name
IL3RA
Full Name
Interleukin-3 receptor subunit alpha
Weight
43.33kDa
Superfamily
type I cytokine receptor family
Alternative Names
CD123 antigen; CD123; hIL3Ra; hIL-3Ra; IL-3 R alpha; IL-3 receptor subunit alpha; IL3R alpha; IL-3R alpha; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; MGC34174 IL3RA CD123, IL3RY, IL3RX, IL3RY, hIL-3Ra, IL3RA interleukin 3 receptor subunit alpha interleukin-3 receptor subunit alpha|CD123 antigen|IL-3 receptor subunit alpha|IL-3R subunit alpha|IL-3R-alpha|IL-3RA|interleukin 3 receptor, alpha (low affinity)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL3RA, check out the IL3RA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL3RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD123 Purified IL3RA Monoclonal Antibody (M04307)
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No publications found for M04307
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