Product Info Summary
SKU: | M00925-2 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IP, ICC, WB |
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Product info
Product Name
Anti-Hu CD178 Purified FASLG Monoclonal Antibody
View all Fas Ligand/TNFSF6 Antibodies
SKU/Catalog Number
M00925-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD178 Purified FASLG Monoclonal Antibody (Catalog# M00925-2). Tested in Flow Cytometry, IP, WB, ICC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD178 Purified FASLG Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00925-2)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
NOK-1
Isotype
Mouse IgG1
Immunogen
L5178Y mouse T lymphoma cells expressing recombinant human CD178. The mouse monoclonal antibody NOK-1 recognizes an extracellular epitope of CD178 / Fas-L, an approximately 40 kDa transmembrane glycoprotein expressed on neutrophils, monocytes, and activated T and NK cells.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00925-2 is reactive to FASLG in Human
Applications
M00925-2 is guaranteed for Flow Cytometry, IP, ICC, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
31.485kDa
Background of Fas Ligand/TNFSF6
CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 µg/ml
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For FASLG (Source: Uniprot.org, NCBI)
Gene Name
FASLG
Full Name
Tumor necrosis factor ligand superfamily member 6
Weight
31.485kDa
Superfamily
tumor necrosis factor family
Alternative Names
apoptosis (APO-1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1CD95L; APTL; CD178 antigen; CD178; CD95L; CD95-L; Fas antigen ligand; Fas ligand (TNF superfamily, member 6); Fas Ligand; FASLCD95 ligand; FASLG; TNFSF6; TNFSF6FasL; tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6 FASLG ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A Fas ligand tumor necrosis factor ligand superfamily member 6|CD95 ligand|Fas ligand (TNF superfamily, member 6)|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|mutant tumor necrosis factor family member 6|tumor necrosis factor ligand 1A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FASLG, check out the FASLG Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FASLG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD178 Purified FASLG Monoclonal Antibody (M00925-2)
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No publications found for M00925-2
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