Anti-Hu CD38 Purified Monoclonal Antibody

CD38 antibody

Boster Bio Anti-Hu CD38 Purified Monoclonal Antibody (Catalog# M00193-1). Tested in Flow Cytometry, WB, IHC-P, IHC-F application(s). This antibody reacts with Human.

Product Info Summary

SKU: M00193-1
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IHC-P, IHC-F, WB

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Product Name

Anti-Hu CD38 Purified Monoclonal Antibody

View all CD38 Antibodies

SKU/Catalog Number

M00193-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD38 Purified Monoclonal Antibody (Catalog# M00193-1). Tested in Flow Cytometry, WB, IHC-P, IHC-F application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD38 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00193-1)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

HIT2

Isotype

Mouse IgG1

Immunogen

Human thymocytes in foetus. The mouse monoclonal antibody HIT2 reacts with an extracellular epitope of CD38, a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells. Its binding is blocked by daratumumab.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00193-1 is reactive to CD38 in Human

Applications

M00193-1 is guaranteed for Flow Cytometry, IHC-P, IHC-F, WB Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

34.328kDa

Background of CD38

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (paraffin sections): 10 μg/ml.
Western blotting: 2 μg/ml; positive control: RAJI human cell line, non-reducing conditions.
Flow cytometry: 1-4 µg/ml

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For CD38 (Source: Uniprot.org, NCBI)

Gene Name

CD38

Full Name

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Weight

34.328kDa

Superfamily

ADP-ribosyl cyclase family

Alternative Names

ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10 CD38 ADPRC 1, ADPRC1 CD38 molecule ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|2-phospho-ADP-ribosyl cyclase|2-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|CD38 antigen (p45)|NAD(+) nucleosidase|cluster of differentiation 38|cyclic ADP-ribose hydrolase 1|ecto-nicotinamide adenine dinucleotide glycohydrolase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CD38, check out the CD38 Infographic

CD38 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD38: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M00193-1

0.1 mg

$298

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