Anti-Human CD98 Purified Monoclonal Antibody

Product Name

Anti-Human CD98 Purified Monoclonal Antibody

View all SLC7A5 Antibodies

SKU/Catalog Number

M01016

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Human CD98 Purified Monoclonal Antibody (Catalog# M01016). Tested in Flow Cytometry, IP, IHC-P application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Human CD98 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01016)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

MEM-108

Isotype

Mouse IgG1

Immunogen

RAJI human Burkitt's lymphoma cell line. The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.

Reactive Species

M01016 is reactive to SLC7A5 in Human

Observed Molecular Weight

42 kDa

Calculated molecular weight

55.0 kDa

Background of SLC7A5

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

M01016 is guaranteed for Flow Cytometry, IP, IHC-P Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 4 μg/ml.
Immunohistochemistry (paraffin sections): 10 μg/ml; positive tissue: liver.

Validation Images & Assay Conditions

See full target information SLC7A5

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis