Anti-Human CD28 Monoclonal Antibody PE Conjugated, Flow Validated

SKU FC00065-PE
Size 25 tests, 100 tests
Reactivity Human
Clonality Monoclonal
Clone Number CD28.2
Host Mouse
Ig Isotype MouseIgG1, kappa
Applications Flow Cytometry, IHC

Overview

Product Name Anti-Human CD28 Monoclonal Antibody PE Conjugated, Flow Validated
SKU/Catalog Number FC00065-PE
Storage & Handling The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Size 25 tests, 100 tests
Description MouseIgG1, kappa Monoclonal Anti-Human CD28 Antibody PE Conjugated, Flow Validated
Cite This Product Anti-Human CD28 Monoclonal Antibody PE Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00065-PE)
Host Mouse
Immunogen [immunogen]
Reactivity Human

Assay Details

Assay Dilutions Overview

Flow Cytometry, 5μl per sample

Images And Assay Conditions

/F/C/FC00065 PE flow cytometry test PE Anti Human CD28 CD28.2.jpg

Human peripheral blood lymphocytes were stained with PE CD28.2 with relevant isotype control in Red.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P10747
Gene Name CD28
Protein Name T-cell-specific surface glycoprotein CD28
Tissue Specificity Expressed in T-cells and plasma cells, but not in less mature B-cells.
Alternative Names T-cell-specific surface glycoprotein CD28;TP44;CD28;CD28;
Subcellular Localization Membrane; Single-pass type I membrane protein.
Molecular Weight 25066 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). .

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Promotion:

Buy primary get secondary antibody for free.
Option Price
500μg $377
100 tests $180
Ships in 5-7 business days.

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