Anti- CD28 Monoclonal Antibody

CD28 antibody

Boster Bio Anti- CD28 Monoclonal Antibody catalog # M00065-1. Tested in IHC-P applications. This antibody reacts with Mouse. Cited in 1 publication(s).

Product Info Summary

SKU: M00065-1
Size: 100μg/vial
Reactive Species: Mouse
Host: Mouse
Application: IHC-P

Product Name

Anti- CD28 Monoclonal Antibody

View all CD28 Antibodies

SKU/Catalog Number

M00065-1

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti- CD28 Monoclonal Antibody catalog # M00065-1. Tested in IHC-P applications. This antibody reacts with Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti- CD28 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00065-1)

Host

Mouse

Contents

PBS, pH 7.0. Contains no stabilizers or preservatives

Clonality

Monoclonal

Clone Number

AGOA-3

Isotype

Mouse IgG1, κ

Immunogen

A20 cells expressing mouse CD28 and a recombinant mouse CD28-Ig fusion protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M00065-1 is reactive to CD28 in Mouse

Applications

M00065-1 is guaranteed for IHC-P Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

25.066kDa

Background of CD28

CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co- stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). The CD28 gene is mapped to 2q33-q34. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For CD28 (Source: Uniprot.org, NCBI)

Gene Name

CD28

Full Name

T-cell-specific surface glycoprotein CD28

Weight

25.066kDa

Alternative Names

CD28 antigen (Tp44); CD28 antigen; CD28 molecule; CD28; MGC138290; T-cell-specific surface glycoprotein CD28; Tp44 CD28 Tp44 CD28 molecule T-cell-specific surface glycoprotein CD28

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CD28, check out the CD28 Infographic

CD28 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD28: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

M00065-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Combination of Chidamide-Mediated Epigenetic Modulation with Immunotherapy: Boosting Tumor Immunogenicity and Response to PD-1/PD-L1 Blockade

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Order DetailsPrice
M00065-1-carrier-free

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$299

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