Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated

Product Name

Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated

View all CD55/DAF Antibodies

SKU/Catalog Number

FC00910-PE

Size

100 tests, 200 tests

Form

Liquid

Description

Boster Bio Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated (Catalog# FC00910-PE). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00910-PE)

Host

Mouse

Contents

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: F4-29D9

Isotype

IgG1,k

Immunogen

Human umbilical vein endothelial cells (HUVEC)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC00910-PE is reactive to CD55 in Human

Applications

FC00910-PE is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

41.4kDa

Background of CD55/DAF

Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

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Monocytes gated human PBMCs stained with antihuman CD55 PE (clone F4-29D9, red histogram). Blue histogram is for the monocytes gated PBMCs stained with IgG1 (MOPC31C) PE conjugated isotype control.

Gene/Protein Information For CD55 (Source: Uniprot.org, NCBI)

Alternative Names

CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CD55; CR; CRdecay accelerating factor for complement (CD55, Cromer blood group system); CROMDAFcomplement decay-accelerating factor; DAF; decay accelerating factor for complement; TC CD55 CHAPLE, CR, CROM, DAF, TC CD55 molecule (Cromer blood group) complement decay-accelerating factor|CD55 antigen|CD55 molecule, decay accelerating factor for complement (Cromer blood group)|Cromer blood group antigen|Rh blood group D antigen

For more info on CD55, check out the CD55 Infographic

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In this infographic, you will see the following information for CD55: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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