Product Info Summary
SKU: | FC00652-PE-Cy7 |
---|---|
Size: | 100 tests, 200 tests |
Reactive Species: | Human, Baboon |
Host: | Mouse |
Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human CD62L Sell Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated
View all L-Selectin/CD62L Antibodies
SKU/Catalog Number
FC00652-PE-Cy7
Size
100 tests, 200 tests
Form
Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA
Description
Boster Bio Anti-Human CD62L Sell Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Catalog# FC00652-PE-Cy7). Tested in Flow Cytometry application(s). This antibody reacts with Human, Baboon.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Human CD62L Sell Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00652-PE-Cy7)
Host
Mouse
Contents
PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Clonality
Monoclonal
Clone Number
Clone: DREG56
Isotype
IgG1,k
Immunogen
PMA-activated human peripheral blood leukocytes
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC00652-PE-Cy7 is reactive to SELL in Human, Baboon
Applications
FC00652-PE-Cy7 is guaranteed for Flow Cytometry Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
42.187kDa
Background of L-Selectin/CD62L
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
Click image to see more details
Lymphocytes gated RBC lysed whole blood stained with PE-Cyanine7 conjugated anti-human CD62L (clone DREG56) (red histogram). Lymphocytes gated RBC lysed whole blood stained with mouse IgG1 (clone MOPC-31) sotype control (blue histogram). The data is generated by BD Accuri C6 Flow Cytometer and analyzed by FlowJo software.
Protein Target Info & Infographic
Gene/Protein Information For SELL (Source: Uniprot.org, NCBI)
Gene Name
SELL
Full Name
L-selectin
Weight
42.187kDa
Superfamily
selectin/LECAM family
Alternative Names
CD62L antigen; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LAM1LECAM1; LECAM1; LEU8; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LNHRTQ1; LSEL; L-Selectin; LYAM1; Lyam-1; LYAM1CD62 antigen-like family member L; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L; SELL; TQ1 SELL CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1 selectin L L-selectin|CD62 antigen-like family member L|gp90-MEL|leukocyte surface antigen Leu-8|leukocyte-endothelial cell adhesion molecule 1|lymph node homing receptor|lymphocyte adhesion molecule 1|pln homing receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SELL, check out the SELL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SELL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human CD62L Sell Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (FC00652-PE-Cy7)
Hello CJ!
FC00652-PE-Cy7 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes
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