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- Table of Contents
L-selectin Antibodies
AND SELL ELISA kits, L-selectin Proteins
Many biological assays use antibodies to detect L-selectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with L-selectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop L-selectin antibodies...
Designing a Western blot for L-selectin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SELL Western Blot GuideSELL Infographic by Boster Bio
All SELL Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK0504
96 wells/kit, with removable strips.
Cat # EK0504
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0504
96 wells/kit, with removable strips.
Cat # FEK0504
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0503
96 wells/kit, with removable strips.
Cat # EK0503
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0503
For 5 plates, 96 wells each
Cat # EZ0503
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # FEK0503
96 wells/kit, with removable strips.
Cat # FEK0503
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00652-3
100 μg
Cat # M00652-3
100 μg
SELL Overview
Facts about L-selectin.
L-selectin (SELL)
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes.
Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SELL |
| Uniprot: | P14151 |
| Entrez: | 6402 |
Family
| Belongs to: |
|---|
| selectin/LECAM family |
Alternative Names
CD62L antigen; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LAM1LECAM1; LECAM1; LEU8; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LNHRTQ1; LSEL; L-Selectin; LYAM1; Lyam-1; LYAM1CD62 antigen-like family member L; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L; SELL; TQ1
Molecular Weight
Mass (kDA):
42.187 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q24.2 |
| Sequence: | 1; NC_000001.11 (169690667..169711620, complement) |
Tissue Specificity
Expressed in B-cell lines and T-lymphocytes.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Malignant Neoplasms
- Tissue Adhesions
- Mental Disorders
- Inflammation
- Neoplasms
- Atherosclerosis
- Spinal Cord Injuries
- Carcinoma
- Lymphoma
- Inflammatory Response
- Streptococcal Infections
- Psychotic Disorders
- Spinal Injuries
Pathways
- Pathogenesis
- Immune Response
- Cell Activation
- Inflammatory Response
- Cell Adhesion
- Aging
- Proteolysis
- Innate Immune Response
- Cell Proliferation
- Endothelial Cell Activation
- Cell Growth
- Transport
- Diapedesis
PTMs
- Phosphorylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SELL
bosterbio.com/bosterbio-gene-info-cards/SELL
References
PMID: 2664786 by Siegelman M.H., et al. Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.
PMID: 2473156 by Tedder T.F., et al. Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.
5 Publications of Boster L-selectin Antibodies & ELISA Kits
- PubMed ID: 10.1177/1535370214542072, Effects of hypercapnia on T cells in lung ischemia/reperfusion injury after lung...
- PubMed ID: 10.1128/JVI.00611-15, HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To I...
- PubMed ID: 33253822, Pearse DD, Anthony Otero P, Diaz A, Pan X, Ghosh M. Neuronal and endothelial tra...
- PubMed ID: 25822027, HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To I...
- PubMed ID: 22391529, Zhong M, He B, Yang J, Bao R, Zhang Y, Zhou D, Chen Y, Li L, Han C, Yang Y, Sun ...
*More publications can be found for each product on its corresponding product page