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Product Info Summary
| SKU: | A14973 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-IA-6 INSM2 Antibody
SKU/Catalog Number
A14973
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IA-6 INSM2 Antibody (Catalog # A14973). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IA-6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-IA-6 INSM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14973)
Host
Rabbit
Contents
IA-6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
IA-6 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IA-6. The immunogen is located within amino acids 340 - 390 of IA-6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two isoforms of IRGC are known to exist; this antibody will recognize both isoforms.
Reactive Species
A14973 is reactive to Insm2 in Human, Mouse, Rat
Applications
A14973 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
52.225kDa
Background of Insm2
IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IA-6 in rat thymus tissue lysate with IA-6 antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Insm2 (Source: Uniprot.org, NCBI)
Gene Name
Insm2
Full Name
Insulinoma-associated protein 2
Weight
52.225kDa
Alternative Names
insulinoma-associated 2; Nbla106; zinc finger protein IA-6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Insm2, check out the Insm2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Insm2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IA-6 INSM2 Antibody (A14973)
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