Anti-Interleukin-13 IL13 Antibody
Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB in Rat. Cited in 6 publication(s).
Anti-Interleukin-13 IL13 Antibody Info At A Glance
|Product Name||Anti-Interleukin-13 IL13 Antibody
See all IL-13 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for IL 13/IL13 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Rat. IL 13/IL13 information: Molecular Weight: 14093 MW; Subcellular Localization: Secreted.|
|Cite This Product||Anti-Interleukin-13 IL13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1469)|
|Similar Products From
|Anti-Interleukin-13 IL13 Antibody may replace the following items: sc 134481|sc 7301|sc 31153|sc 52349|sc 377344|sc 284|sc 31154|sc 374382|sc 393712|sc 08|sc 136294|sc 71667|sc 23864|sc 33684|sc 284 G.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence in the middle region of rat IL-13(80-102aa CNAIHRTQRILNGLCNQKASDVA).|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For Il13 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||116553|
|Species Of This Entry||Rat|
|Alternative Names||IL-13|ALRHMGC116789; BHR1interleukin-13; IL13; IL-13; IL-13MGC116788; interleukin 13; MGC116786; NC30; P600|
|Post Tranlational Modifications||Methylation; Phosphorylation; Acetylation; Demethylation; Cleavage|
|Gene Location||10q22, on Chromasome 10, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For Il13 (Source: Uniprot.org, NCBI)
|Protein Function||Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages.|
|Related Diseases||Asthma; Inflammation; Allergy; Neoplasms; Malignant Neoplasms; Glioma; Dysequilibrium Syndrome; Immediate Hypersensitivity; Arthritis; Dermatitis, Atopic; Psoriasis; Allergic Asthma; Rhinorrhea; Lung Diseases; Autoimmune Reaction; Autoimmune Diseases; Glioblastoma; Brain Neoplasms; Childhood Asthma; Dermatitis|
|Related Pathways||Pathogenesis; Immune Response; Sensitization; Cytokine Production; Secretion; Hypersensitivity; Cell Differentiation; Cell Activation; Methylation; Cell Adhesion; T Cell Activation; Cell Proliferation; Inflammatory Response; Reverse Transcription; Tissue Remodeling; Anaphylaxis; Dna Methylation; Macrophage Activation; Localization; Rna Interference|
|Background||IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2(Th2) cells that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor(IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.|
|Scientific References||PMID: 7916615 by Lakkis F.G., et al. Cloning of rat interleukin-13 (IL-13) cDNA and analysis of IL-13 gene expression in experimental glomerulonephritis.|
Our Boster Quality Guarantee for Anti-Interleukin-13 IL13 Antibody covers its use in the following applications.Western blot, 0.1-0.5μg/ml, Rat
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
All lanes: Anti IL-13 (PA1469) at 0.5ug/ml
Lane 1: Recombinant Rat IL-13 Protein 5ng
Lane 2: Recombinant Rat IL-13 Protein 2.5ng
Predicted bind size: 13KD
Observed bind size: 13KD
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Total number of citations: 6
|Wang B, Liang S, Wang Y, Zhu Xq, Gong W, Zhang Hq, Li Y, Xia Cm. Plos Negl Trop Dis. 2015 Jan 15;9(1):E0003434. Doi: 10.1371/Journal.Pntd.0003434. Ecollection 2015. Th17 Down-Regulation Is Involved In Reduced Progression Of Schistosomiasis Fibrosi...||PubMed ID 25590646|
|Li J, Li L, Zuo H, Ke C, Yan B, Wen H, Zhang Y, Yang X. Plos One. 2014 Feb 3;9(2):E87887. Doi: 10.1371/Journal.Pone.0087887. Ecollection 2014. T-Helper Type-2 Contact Hypersensitivity Of Balb/C Mice Aggravated By Dibutyl Phthalate Via Long-Term De...||PubMed ID 24498391|
|CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction||PubMed ID 26771842|
|An IL-13 Promoter Polymorphism Associated with Liver Fibrosis in Patients with Schistosoma japonicum||PubMed ID 26258681|
|Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats||PubMed ID 29541141|
|Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice||PubMed ID 30090343|
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Note: sample size takes longer to process, average 5-7 days.
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