Anti-Interleukin-2 IL2 Antibody
Rabbit IgG polyclonal antibody for Interleukin-2(IL2) detection. Tested with WB in Mouse. Cited in 8 publication(s).
Anti-Interleukin-2 IL2 Antibody Info At A Glance
|Product Name||Anti-Interleukin-2 IL2 Antibody
See all IL-2 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for IL 2/IL2 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Mouse. IL 2/IL2 information: Molecular Weight: 19400 MW; Subcellular Localization: Secreted.|
|Cite This Product||Anti-Interleukin-2 IL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1466)|
|Similar Products From
|Anti-Interleukin-2 IL2 Antibody may replace the following items: sc 163885.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL-2(151-169aa DFLRRWIAFCQSIISTSPQ).|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For Il2 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||16183|
|Species Of This Entry||Mouse|
|Alternative Names||IL-2|Aldesleukin; IL2; IL-2; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF|
|Post Tranlational Modifications||Phosphorylation; Acetylation; Methylation; Cleavage; Glycosylation; Reduction; Dephosphorylation; Demethylation; Biotinylation; Oxidation; Ribosylation; Nitration; Deacetylation; Ubiquitination|
|Gene Location||3 B|3 18.3 cM, on Chromasome 3, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For Il2 (Source: Uniprot.org, NCBI)
|Protein Function||Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.|
|Related Diseases||Neoplasms; Malignant Neoplasms; Leukemia; Autoimmune Reaction; Carcinoma; Inflammation; Lymphoma; Melanoma; Autoimmune Diseases; Immunologic Deficiency Syndromes; Decreased Immunologic Activity [pe]; Malignant Paraganglionic Neoplasm; Infective Disorder; Neoplasm Metastasis; Hiv Infections; Diabetes Mellitus; Diabetes Mellitus, Insulin-dependent; Renal Cell Carcinoma; Kidney Neoplasm; Arthritis|
|Related Pathways||Immune Response; Secretion; Cell Activation; Cell Proliferation; T Cell Activation; Pathogenesis; Cell Growth; Cytokine Production; T Cell Proliferation; Lymphocyte Proliferation; Cell Cycle; Lymphocyte Activation; Cell Differentiation; Cell Death; Hypersensitivity; Localization; B Cell Differentiation; Cell Development; Aging; Inflammatory Response|
|Background||IL-2, Interleukin-2, formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin-or antigen-activated T cells. In situ hybridization, the IL-2 gene is assigned to 4q26-q28. IL2 can act as a growth hormone for both B and T lymphocytes. It is useful in the study of the molecular nature of T-cell differentiation and, like interferons, augments natural killer cell activity.|
|Scientific References||PMID: 6240025 by Fuse A., et al. Organization and structure of the mouse interleukin-2 gene.|
PMID: 2578624 by Kashima N., et al. Unique structure of murine interleukin-2 as deduced from cloned cDNAs.
Our Boster Quality Guarantee for Anti-Interleukin-2 IL2 Antibody covers its use in the following applications.Western blot, 0.1-0.5μg/ml, Mouse
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Lane 1: Recombinant Mouse IL-2 Protein 10ng
Lane 2: Recombinant Mouse IL-2 Protein 5ng
Lane 3: Recombinant Mouse IL-2 Protein 2.5ng
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Total number of citations: 8
|Hu W,, Jing P, Wang L, Zhang Y, Yong J, Wang Y. Bmc Complement Altern Med. 2015 Apr 15;15:119. Doi: 10.1186/S12906-015-0642-3. The Positive Effects Of Ginsenoside Rg1 Upon The Hematopoietic Microenvironment In A D-Galactose-Induced Aged Rat Model.||PubMed ID 25881060|
|Xie Ft, Cao Js, Zhao J, Yu Y, Qi F, Dai Xc. Transpl Immunol. 2015 Oct;33(2):69-77. Doi: 10.1016/J.Trim.2015.05.003. Epub 2015 May 20. Ido Expressing Dendritic Cells Suppress Allograft Rejection Of Small Bowel Transplantation In Mice By Expansion O...||PubMed ID 26002283|
|Gong T, Wang Cf, Yuan Jr, Li Y, Gu Jf, Zhao Bj, Zhang L, Jia Xb, Feng L, Liu Sl. Evid Based Complement Alternat Med. 2015;2015:630760. Doi: 10.1155/2015/630760. Epub 2015 May 3. Inhibition Of Tumor Growth And Immunomodulatory Effects Of Flavonoids...||PubMed ID 26064167|
|Chen B, Liu L, Xu H, Yang Y, Zhang L, Zhang F. Exp Ther Med. 2015 Mar;9(3):1063-1067. Epub 2015 Jan 26. Effectiveness Of Immune Therapy Combined With Chemotherapy On The Immune Function And Recurrence Rate Of Cervical Cancer.||PubMed ID 25667679|
|Zhong B, Shen H, Sun X, Wang H, Zhang Y, Sun Z. Cancer Biother Radiopharm. 2012 May;27(4):252-8. Doi: 10.1089/Cbr.2011.1105. Additive Effects Of Ulinastatin And Docetaxel On Growth Of Breast Cancer Xenograft In Nude Mice And Expression Of Pge2, Il...||PubMed ID 22594905|
|Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells||PubMed ID 27284330|
|Women with Recurrent Miscarriage Have Decreased Expression of 25-Hydroxyvitamin D3-1?-Hydroxylase by the Fetal-Maternal Interface||PubMed ID 28902929|
|Positive effects of porcine IL-2 and IL-4 on virus-specific immune responses induced by the porcine reproductive and respiratory syndrome virus (PRRSV) %u2026||PubMed ID 24136204|
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Note: sample size takes longer to process, average 5-7 days.
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