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- Table of Contents
IL31 antibody (A08339) performs well in ELISA, IHC-P, WB and shows reactivity with Mouse.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunohistochemistry of IL-31 in rat skeletal muscle tissue with IL-31 antibody at 10 μg/mL.
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Anti-IL-31 Antibody
IL31 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Mouse | Rabbit | ELISA, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
IL-31 antibody can be used for the detection of IL-31 by Western blot at 2.5 - 10 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-IL-31 Antibody
View all IL31 Antibodies
View all IL31 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
IL-31 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
IL-31 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IL-31 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31. The immunogen is located within amino acids 30 - 80 of IL-31.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
18.1 kDa
Background of IL31
Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
Cite This Product
Anti-IL-31 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08339)
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Product Promise
We promise Anti-IL-31 Antibody performs excellently in relevant applications for ELISA, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A08339
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 1, 2026