Product Info Summary
SKU: | M00651-1 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Rat |
Host: | Mouse |
Application: | ELISA |
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Product info
Product Name
Anti-IL1RA Antibody Picoband™ (monoclonal, 12C13)
View all IL-1ra/IL-1F3/IL1RN Antibodies
SKU/Catalog Number
M00651-1
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-IL1RA Antibody Picoband™ (monoclonal, 12C13) catalog # M00651-1. Tested in ELISA applications. This antibody reacts with Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IL1RA Antibody Picoband™ (monoclonal, 12C13) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00651-1)
Host
Mouse
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Clonality
Monoclonal
Clone Number
12C13
Isotype
Mouse IgG2b
Immunogen
E. coli-derived rat IL1RA recombinant protein (Position: H27-Q178). Rat IL1RA shares 77.6% and 90.7% amino acid (aa) sequence identity with human and mouse IL1RA, respectively.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
M00651-1 is reactive to IL1RN in Rat
Applications
M00651-1 is guaranteed for ELISA Boster Guarantee
Observed Molecular Weight
100-110 kDa
Calculated molecular weight
20.055kDa
Background of IL-1ra/IL-1F3/IL1RN
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA (Cap), 1-5μg/ml, Rat
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For IL1RN (Source: Uniprot.org, NCBI)
Gene Name
IL1RN
Full Name
Interleukin-1 receptor antagonist protein
Weight
20.055kDa
Alternative Names
DIRA; ICIL-1ra; IL1F3; IL-1F3; IL1ra; IL-1ra; IL-1ra3; IL1RN; IL-1RN; interleukin 1 receptor antagonist; IRAP; MVCD4 IL1RN DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4 interleukin 1 receptor antagonist interleukin-1 receptor antagonist protein|IL1 inhibitor|intracellular IL-1 receptor antagonist type II|intracellular interleukin-1 receptor antagonist (icIL-1ra)|type II interleukin-1 receptor antagonist
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL1RN, check out the IL1RN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL1RN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL1RA Antibody Picoband™ (monoclonal, 12C13) (M00651-1)
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No publications found for M00651-1
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