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Product Info Summary
| SKU: | M00651-1 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Rat |
| Host: | Mouse |
| Application: | ELISA (Cap) |
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Product info
Product Name
Anti-IL1RA Antibody (monoclonal, 12C13)
SKU/Catalog Number
M00651-1
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-IL1RA Antibody (monoclonal, 12C13) catalog # M00651-1. Tested in ELISA applications. This antibody reacts with Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IL1RA Antibody (monoclonal, 12C13) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00651-1)
Host
Mouse
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Clonality
Monoclonal
Clone Number
12C13
Isotype
Mouse IgG2b
Immunogen
E. coli-derived rat IL1RA recombinant protein (Position: H27-Q178). Rat IL1RA shares 77.6% and 90.7% amino acid (aa) sequence identity with human and mouse IL1RA, respectively.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
M00651-1 is reactive to Il1rn in Rat
Calculated molecular weight
20.3 kDa
Background of Il1rn
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00651-1 is guaranteed for ELISA (Cap) Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA (Cap), 1-5μg/ml, Rat
Validation Images & Assay Conditions
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Specific Publications For Anti-IL1RA Antibody (monoclonal, 12C13) (M00651-1)
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