Interleukin-1 receptor antagonist protein (IL1RN)

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for indicating. Has no interleukin-1 like activity.

Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2nonetheless, the physiological relevance of the latter institution is unsure. .