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- Table of Contents
IL1RN Antibodies
AND IL1RN ELISA kits, IL1RN Proteins
Many biological assays use antibodies to detect IL1RN, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL1RN in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL1RN antibodies...
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IL1RN Infographic by Boster Bio
All IL1RN Products
Product
Figures
Specificity
Applications
Price
Human IL-1RA/IL1RN ELISA Kit PicoKine®
3 Citations 7 Q&As
Human
ELISA
$499
Cat # EK0782
96 wells/kit, with removable strips.
Cat # EK0782
96 wells/kit, with removable strips.
Mouse IL-1RA/IL1RN ELISA Kit PicoKine®
5 Citations 4 Q&As
Mouse
ELISA
$499
Cat # EK0783
96 wells/kit, with removable strips.
Cat # EK0783
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00651-2
100 μg/vial
Cat # A00651-2
100 μg/vial
Anti-IL1RA Rabbit Monoclonal Antibody
1 Citations 3 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00651
100 μl
Cat # M00651
100 μl
Human
ELISA
$500
Cat # EZ0782
For 5 plates, 96 wells each
Cat # EZ0782
For 5 plates, 96 wells each
Mouse
ELISA
$500
Cat # EZ0783
For 5 plates, 96 wells each
Cat # EZ0783
For 5 plates, 96 wells each
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00651-5
100 μg/vial
Cat # A00651-5
100 μg/vial
SDS-PAGE, Bioactivity
$243
Cat # PROTP25085
Starting from 10ug
Cat # PROTP25085
Starting from 10ug
Human
ELISA
$499
Cat # FEK0782
96 wells/kit, with removable strips.
Cat # FEK0782
96 wells/kit, with removable strips.
Human
IHC, WB
$523
Cat # M00651-2
100 µl
Cat # M00651-2
100 µl
Human
Cell Culture
$77
Cat # PROTP18510-5
20ug,100ug,500ug
Cat # PROTP18510-5
20ug,100ug,500ug
Mouse
Cell Culture
$77
Cat # PROTP25085-3
5ug,20ug,100ug
Cat # PROTP25085-3
5ug,20ug,100ug
Porcine
ELISA
$499
Cat # EK2358
96 wells/kit, with removable strips.
Cat # EK2358
96 wells/kit, with removable strips.
IL1RN Overview
Facts about Interleukin-1 receptor antagonist protein.
Interleukin-1 receptor antagonist protein (IL1RN)
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for indicating. Has no interleukin-1 like activity.
Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2nonetheless, the physiological relevance of the latter institution is unsure. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IL1RN |
| Uniprot: | P18510 |
| Entrez: | 3557 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DIRA; ICIL-1ra; IL1F3; IL-1F3; IL1ra; IL-1ra; IL-1ra3; IL1RN; IL-1RN; interleukin 1 receptor antagonist; IRAP; MVCD4
Molecular Weight
Mass (kDA):
20.055 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.1 |
| Sequence: | 2; NC_000002.12 (113099365..113134016) |
Tissue Specificity
The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Subcellular Localizations
[Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
Diseases
- Inflammation
- Arthritis
- Rheumatoid Arthritis
- Variable Number Tandem Repeat
- Malignant Neoplasms
- Inflammatory Response
- Systemic Infection
- Infective Disorder
- Autoimmune Reaction
- Neoplasms
- Tissue Adhesions
- Degenerative Polyarthritis
- Autoimmune Diseases
Interacting Proteins
- TERF2IP
Pathways
- Pathogenesis
- Secretion
- Inflammatory Response
- Cytokine Production
- Immune Response
- Bone Resorption
- Cell Proliferation
- Localization
- Cell Adhesion
- Translation
- Cell Death
- Cell Activation
- Cell Growth
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Reduction
- Oxidation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL1RN
bosterbio.com/bosterbio-gene-info-cards/IL1RN
References
PMID: 2139180 by Carter D.B., et al. Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein.
PMID: 2137201 by Eisenberg S.P., et al. Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist.
7 Publications of Boster IL1RN Antibodies & ELISA Kits
- PubMed ID: 10.3389/fcell.2020.00703, Bergenin as a Novel Urate-Lowering Therapeutic Strategy for Hyperuricemia
- PubMed ID: 10.1080/1028415X.2016.1189057, Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α ...
- PubMed ID: 10.1016/j.imlet.2014.08.003, Involvement of IL-6 and IL-1 receptor antagonist on intellectual disability
- PubMed ID: 10.1016/j.ejphar.2019.03.031, rhIL-1Ra reduces hepatocellular apoptosis in mice with acute liver failure mainl...
- PubMed ID: 29942332, The effect of salusin-? on expression of pro- and anti-inflammatory cytokines in...
- PubMed ID: 25267210, TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integratin...
- PubMed ID: 2922315, Esfahani, M., Saidijam, M., Goodarzi, M.T., Movahedian, A., & Najafi, R. (2017)....
*More publications can be found for each product on its corresponding product page