Anti-Importin subunit alpha-8 KPNA7 Antibody

Product Name

Anti-Importin subunit alpha-8 KPNA7 Antibody

View all KPNA7 Antibodies

SKU/Catalog Number

A11830

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Importin subunit alpha-8 KPNA7 Antibody (Catalog # A11830). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.

Storage & Handling

KPNA7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Importin subunit alpha-8 KPNA7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11830)

Host

Rabbit

Contents

KPNA7 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

KPNA7 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA7. The immunogen is located within amino acids 40 - 90 of KPNA7.

Cross-reactivity

KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members.

Reactive Species

A11830 is reactive to KPNA7 in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

56.9 kDa

Background of KPNA7

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A11830 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

KPNA7 antibody can be used for detection of KPNA7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information KPNA7

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