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Product Info Summary
| SKU: | A12113 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-Iporin RUSC2 Antibody
SKU/Catalog Number
A12113
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Iporin RUSC2 Antibody (Catalog # A12113). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Iporin RUSC2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12113)
Host
Rabbit
Contents
RUSC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2. The immunogen is located within amino acids 1410 - 1460 of RUSC2.
Cross-reactivity
At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.
Reactive Species
A12113 is reactive to RUSC2 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
161.2 kDa
Background of RUSC2
RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12113 is guaranteed for ELISA, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of RUSC2 in human placenta tissue with RUSC2 antibody at 5 μg/mL.
Specific Publications For Anti-Iporin RUSC2 Antibody (A12113)
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