Anti-IRX3 Antibody

Product Name

Anti-IRX3 Antibody

View all Irx3 Antibodies

SKU/Catalog Number

A07258

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-IRX3 Antibody (Catalog # A07258). Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IRX3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07258)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human IRX3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07258 is reactive to Irx3 in Human, Mouse

Applications

A07258 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

52.693kDa

Background of Irx3

Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity.

Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using IRX3 antibody A07258.

Gene/Protein Information For Irx3 (Source: Uniprot.org, NCBI)

Alternative Names

Homeodomain protein IRXB1; iroquois homeobox 3; Iroquois homeobox protein 3; iroquois-class homeodomain protein IRX-1; iroquois-class homeodomain protein IRX-3; IRX-1; IRXB1FLJ99187 Irx3|AI894186|Iroquois related homeobox 3|iroquois-class homeodomain protein IRX-3|homeodomain protein IRXB1|iroquois homeobox protein 3

For more info on Irx3, check out the Irx3 Infographic

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In this infographic, you will see the following information for Irx3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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