Anti-Kallikrein 2/KLK2 Antibody
Rabbit IgG polyclonal antibody for Kallikrein-2(KLK2) detection. Tested with WB, IHC-P in Human.
Anti-Kallikrein 2/KLK2 Antibody Info At A Glance
|Product Name||Anti-Kallikrein 2/KLK2 Antibody
See all Kallikrein 2 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for Kallikrein 2/KLK2 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Kallikrein 2/KLK2 information: Molecular Weight: 28671 MW; .|
|Cite This Product||Anti-Kallikrein 2/KLK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1626)|
|Similar Products From
|Anti-Kallikrein 2/KLK2 Antibody may replace the following items: sc 20368|sc 20370.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 2(243-261aa YTKVVHYRKWIKDTIAANP).|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For KLK2 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||3817|
|Species Of This Entry||Human|
|Superfamily||peptidase S1 family|
|Alternative Names||Kallikrein 2|EC 3.4.21; EC 18.104.22.168; glandular kallikrein 2; Glandular kallikrein-1; hGK-1; hK2; Kallikrein 2; kallikrein 2, prostatic; kallikrein-2; kallikrein-related peptidase 2; Klk1c2; KLK2; KLK2A2; MGC12201; Tissue kallikrein-2; Ton|
|Post Tranlational Modifications||Cleavage; Acetylation; Methylation; Phosphorylation; Reduction; Glycosylation|
|Gene Location||19q13.33, on Chromasome 19, gene sequence: NC_000019.10 (50873433..50880567)|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For KLK2 (Source: Uniprot.org, NCBI)
|Protein Function||Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.|
|Related Diseases||Malignant Neoplasms; Malignant Neoplasm Of Prostate; Prostatic Neoplasms; Neoplasms; Malignant Neoplasm Of Breast; Carcinoma; Malignant Paraganglionic Neoplasm; Neoplasm Metastasis; Benign Prostatic Hypertrophy; Prostatic Hyperplasia; Hyperplasia; Cholangiocarcinoma; Mammary Neoplasms; Adenocarcinoma; Carcinogenesis; Tumor Angiogenesis; Malignant Neoplasm Of Ovary; Cell Invasion; Tissue Adhesions|
|Related Pathways||Cell Proliferation; Angiogenesis; Pathogenesis; Proteolysis; Inflammatory Response; Reverse Transcription; Receptor Transactivation; Localization; Methylation; Cell Growth; Secretion; Cell Adhesion; Cell Migration; Aging; Protein Secretion; Fermentation; Translation; Cell Cycle; Histone Acetylation; Mating|
|Background||KLK2(KALLIKREIN 2), also called GLANDULAR or PROSTATIC, is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. The KLK2 is a member of glandular kallikrein gene family that comprises 25 to 30 highly homologous genes that encode specific proteases involved in the processing of biologically active peptides. The KLK2 gene is mapped to 19q13.33. And the KLK2 gene contains 5 exons. An alternative KLK2 transcript, which they call KLK2-linked molecule(KLM), that arises from the use of an alternate donor site within intron 1. KLM shares only the N-terminal 15-amino acid signal peptide with the original KLK2 protein; the mature proteins display no similarity.|
|Scientific References||PMID: 2824146 by Schedlich L.J., et al. Primary structure of a human glandular kallikrein gene.|
PMID: 1726490 by Riegman P.H., et al. Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species.
Our Boster Quality Guarantee for Anti-Kallikrein 2/KLK2 Antibody covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
IHC(P): Human Prostatic Cancer Tissue
All lanes: Anti Kallikrein 2 (PA1626) at 0.5ug/ml
Lane 1: PANC Whole Cell Lysate at 40ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: 293T Whole Cell Lysate at 40ug
Predicted bind size: 29KD
Observed bind size: 29KD
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Note: sample size takes longer to process, average 5-7 days.
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