Anti-Kallikrein 6/KLK6 Antibody Picoband™

Kallikrein 6/Neurosin antibody

Boster Bio Anti-Kallikrein 6/KLK6 Antibody Picoband™ catalog # A01882-2. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A01882-2
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-Kallikrein 6/KLK6 Antibody Picoband™

View all Kallikrein 6/Neurosin Antibodies

SKU/Catalog Number

A01882-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Kallikrein 6/KLK6 Antibody Picoband™ catalog # A01882-2. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kallikrein 6/KLK6 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01882-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human Kallikrein 6 recombinant protein (Position: L22-K244).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01882-2 is reactive to KLK6 in Human

Applications

A01882-2 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

29 kDa

Calculated molecular weight

26.856kDa

Background of Kallikrein 6/Neurosin

KLK6 (Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For KLK6 (Source: Uniprot.org, NCBI)

Gene Name

KLK6

Full Name

Kallikrein-6

Weight

26.856kDa

Superfamily

peptidase S1 family

Alternative Names

Bssp; EC 3.4.21; EC 3.4.21.-; hK6; kallikrein 6 (neurosin, zyme); Kallikrein 6; kallikrein-6; kallikrein-related peptidase 6; KLK6; Klk7; Neurosin; Protease M; protease, serine, 18; PRSS18; PRSS9; PRSS9MGC9355; Serine protease 18; Serine protease 9; SP59; Zyme KLK6 Bssp, Klk7, PRSS18, PRSS9, SP59, hK6 kallikrein related peptidase 6 kallikrein-6|neurosin|protease M|serine protease 18|serine protease 9|zyme

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KLK6, check out the KLK6 Infographic

KLK6 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KLK6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01882-2

100μg

$370
A01882-2-10ug

10μg sample (liquid)

$99
A01882-2-Biotin

100 μg Biotin conjugated

$570
A01882-2-Cy3

100 μg Cy3 conjugated

$570
A01882-2-Dylight488

100 μg Dylight488 conjugated

$570
A01882-2-Dylight550

100 μg Dylight550 conjugated

$570
A01882-2-Dylight594

100 μg Dylight594 conjugated

$570
A01882-2-FITC

100 μg FITC conjugated

$570
A01882-2-HRP

100 μg HRP conjugated

$570
A01882-2-APC

100 μg APC conjugated

$670
A01882-2-PE

100 μg PE conjugated

$670
A01882-2-carrier-free

Carrier Free

$370

More conjugates/formats

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A01882-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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