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Product Info Summary
| SKU: | A05369 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-KCNK5 Antibody
SKU/Catalog Number
A05369
Size
100ul
Form
Liquid
Description
Boster Bio Anti-KCNK5 Antibody catalog # A05369. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KCNK5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05369)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human KCNK5 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05369 is reactive to KCNK5 in Human
Applications
A05369 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
55.13kDa
Background of KCNK5
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For KCNK5 (Source: Uniprot.org, NCBI)
Gene Name
KCNK5
Full Name
Potassium channel subfamily K member 5
Weight
55.13kDa
Superfamily
two pore domain potassium channel (TC 1.A.1.8) family
Alternative Names
Acid-sensitive potassium channel protein TASK-2; FLJ11035; K2p5.1; potassium channel subfamily K member 5; potassium channel, subfamily K, member 1 (TASK-2); potassium channel, subfamily K, member 5; TASK-2; TASK2K2P5.1 potassium channel; TWIK-related acid-sensitive K(+) channel 2; TWIK-related acid-sensitive K+ channel 2 KCNK5 K2p5.1b, TASK-2, TASK2, KCNK5 potassium two pore domain channel subfamily K member 5 potassium channel subfamily K member 5|K2P5.1 potassium channel|TWIK-related acid-sensitive K(+) channel 2|TWIK-related acid-sensitive K+ 2|TWIK-related acid-sensitive K+ channel 2|acid-sensitive potassium channel protein TASK-2|potassium channel, subfamily K, member 1 (TASK-2)|potassium channel, subfamily, member 5 (KCNK5)|potassium channel, two pore domain subfamily K, member 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNK5, check out the KCNK5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNK5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNK5 Antibody (A05369)
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No publications found for A05369
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